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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
6.06
Human Site:
T646
Identified Species:
10.26
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
T646
P
E
P
K
G
D
A
T
P
E
G
E
K
A
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
A563
P
E
P
K
G
D
A
A
P
E
G
E
K
A
T
Dog
Lupus familis
XP_536547
1100
121754
A646
T
E
P
K
E
D
A
A
P
E
E
E
K
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
A646
S
E
P
K
G
D
A
A
R
E
G
E
K
P
D
Rat
Rattus norvegicus
Q63617
999
111271
A646
S
E
P
K
G
D
A
A
R
E
G
E
T
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
N651
P
K
E
E
S
Q
K
N
E
E
G
E
K
S
E
Frog
Xenopus laevis
Q566I3
646
72655
S357
P
V
Q
Q
A
L
A
S
A
E
M
K
M
E
E
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
T657
T
E
K
P
E
E
K
T
T
D
E
E
K
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
F352
Q
S
L
L
Q
E
F
F
H
G
K
N
L
N
L
Honey Bee
Apis mellifera
XP_624153
932
105575
T626
K
E
K
E
K
K
A
T
I
V
T
I
K
E
P
Nematode Worm
Caenorhab. elegans
P09446
640
69704
L351
I
P
K
V
Q
K
L
L
S
D
L
F
S
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
T580
N
I
T
L
E
T
D
T
K
N
T
T
E
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
N576
T
G
N
A
T
D
E
N
S
Q
E
N
K
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
V418
P
D
E
D
T
S
L
V
V
F
N
K
G
N
V
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
66.6
60
N.A.
N.A.
33.3
20
26.6
N.A.
0
26.6
0
N.A.
P-Site Similarity:
100
N.A.
93.3
66.6
N.A.
66.6
60
N.A.
N.A.
53.3
40
40
N.A.
6.6
33.3
6.6
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
50
29
8
0
0
0
0
22
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
43
8
0
0
15
0
0
0
0
22
% D
% Glu:
0
50
15
15
22
15
8
0
8
50
22
50
8
36
15
% E
% Phe:
0
0
0
0
0
0
8
8
0
8
0
8
0
0
0
% F
% Gly:
0
8
0
0
29
0
0
0
0
8
36
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
8
8
22
36
8
15
15
0
8
0
8
15
58
0
8
% K
% Leu:
0
0
8
15
0
8
15
8
0
0
8
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
8
0
8
0
0
0
0
15
0
8
8
15
0
15
0
% N
% Pro:
36
8
36
8
0
0
0
0
22
0
0
0
0
15
8
% P
% Gln:
8
0
8
8
15
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% R
% Ser:
15
8
0
0
8
8
0
8
15
0
0
0
8
8
8
% S
% Thr:
22
0
8
0
15
8
0
29
8
0
15
8
8
0
15
% T
% Val:
0
8
0
8
0
0
0
8
8
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _