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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HYOU1 All Species: 23.03
Human Site: T881 Identified Species: 38.97
UniProt: Q9Y4L1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4L1 NP_001124463.1 999 111335 T881 E Q A K L P A T E K P V L L S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096142 916 102146 T798 E Q A K L P A T E K P V L L S
Dog Lupus familis XP_536547 1100 121754 T881 E Q A K L P A T E K P V L L S
Cat Felis silvestris
Mouse Mus musculus Q9JKR6 999 111163 T881 E Q A K L P A T E K P V L L S
Rat Rattus norvegicus Q63617 999 111271 T881 E Q A K L P A T E K P V L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK7 1002 112301 A886 E Q N K L S P A E K P V L L S
Frog Xenopus laevis Q566I3 646 72655 S536 A H F N M D E S G L L T L D R
Zebra Danio Brachydanio rerio Q7ZUW2 980 110301 T862 E Q E K L S P T V K P V L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INI8 641 70177 R531 A D E D E K H R Q R I T S R N
Honey Bee Apis mellifera XP_624153 932 105575 Y816 S F T E T A L Y E P V K Y K V
Nematode Worm Caenorhab. elegans P09446 640 69704 D530 A E K Y K A D D E A Q K D R I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002322555 881 98313 L763 A R K Y I G E L Q Q I V Q G W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567510 867 96706 L755 A R K Y L T E L K E I I K E W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O74225 707 78655 A597 D D Q Y A D L A S E E E K E K
Conservation
Percent
Protein Identity: 100 N.A. 89 83.3 N.A. 92 91.6 N.A. N.A. 69.1 49.3 65.3 N.A. 24.5 42.4 24.6 N.A.
Protein Similarity: 100 N.A. 90 86 N.A. 95.5 94.7 N.A. N.A. 80.7 56.4 77.4 N.A. 38.7 60 39.5 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 73.3 6.6 73.3 N.A. 0 6.6 6.6 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 73.3 20 73.3 N.A. 20 13.3 13.3 N.A.
Percent
Protein Identity: 29.7 N.A. N.A. 30.7 N.A. 26.5
Protein Similarity: 50.7 N.A. N.A. 49 N.A. 43.1
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 33.3 N.A. N.A. 33.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 0 36 0 8 15 36 15 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 0 8 0 15 8 8 0 0 0 0 8 8 0 % D
% Glu: 50 8 15 8 8 0 22 0 58 15 8 8 0 15 0 % E
% Phe: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 8 0 0 0 0 8 0 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 22 8 0 0 8 % I
% Lys: 0 0 22 50 8 8 0 0 8 50 0 15 15 8 8 % K
% Leu: 0 0 0 0 58 0 15 15 0 8 8 0 58 50 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 36 15 0 0 8 50 0 0 0 0 % P
% Gln: 0 50 8 0 0 0 0 0 15 8 8 0 8 0 0 % Q
% Arg: 0 15 0 0 0 0 0 8 0 8 0 0 0 15 8 % R
% Ser: 8 0 0 0 0 15 0 8 8 0 0 0 8 0 50 % S
% Thr: 0 0 8 0 8 8 0 43 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 8 0 8 58 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % W
% Tyr: 0 0 0 29 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _