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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
38.18
Human Site:
Y231
Identified Species:
64.62
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
Y231
T
A
Q
N
I
M
F
Y
D
M
G
S
G
S
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
Y193
T
A
Q
N
I
M
F
Y
D
M
G
S
G
S
T
Dog
Lupus familis
XP_536547
1100
121754
Y231
T
A
Q
N
V
M
F
Y
D
M
G
S
G
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
Y231
T
A
Q
N
V
M
F
Y
D
M
G
S
G
S
T
Rat
Rattus norvegicus
Q63617
999
111271
Y231
T
A
Q
N
I
M
F
Y
D
M
G
S
G
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
Y226
S
F
Q
N
I
M
F
Y
D
M
G
A
G
S
T
Frog
Xenopus laevis
Q566I3
646
72655
M26
H
T
E
S
V
A
V
M
S
V
D
L
G
S
E
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
Y223
T
A
Q
N
I
M
F
Y
D
M
G
S
G
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
G21
C
V
G
V
Y
Q
H
G
K
V
E
I
I
A
N
Honey Bee
Apis mellifera
XP_624153
932
105575
Y219
T
A
H
Y
V
M
F
Y
D
M
G
A
S
S
T
Nematode Worm
Caenorhab. elegans
P09446
640
69704
V20
T
T
Y
S
C
V
G
V
F
M
H
G
K
V
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
Y226
G
S
R
Y
V
V
F
Y
D
M
G
A
S
S
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
Y222
G
S
R
H
V
I
F
Y
D
M
G
S
S
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
I87
V
A
I
E
Q
Q
F
I
S
A
T
L
V
D
V
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
100
N.A.
N.A.
80
13.3
100
N.A.
0
66.6
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
40
100
N.A.
13.3
80
26.6
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
46.6
N.A.
N.A.
53.3
N.A.
13.3
P-Site Similarity:
80
N.A.
N.A.
86.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
0
8
0
0
0
8
0
22
0
8
0
% A
% Cys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
72
0
8
0
0
8
0
% D
% Glu:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
15
% E
% Phe:
0
8
0
0
0
0
79
0
8
0
0
0
0
0
0
% F
% Gly:
15
0
8
0
0
0
8
8
0
0
72
8
58
0
0
% G
% His:
8
0
8
8
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
36
8
0
8
0
0
0
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% L
% Met:
0
0
0
0
0
58
0
8
0
79
0
0
0
0
0
% M
% Asn:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
8
15
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
15
0
15
0
0
0
0
15
0
0
50
22
79
0
% S
% Thr:
58
15
0
0
0
0
0
0
0
0
8
0
0
0
72
% T
% Val:
8
8
0
8
43
15
8
8
0
15
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
15
8
0
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _