KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
23.94
Human Site:
Y534
Identified Species:
40.51
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
Y534
S
F
K
K
Y
P
D
Y
E
S
K
G
I
K
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
Y451
S
F
K
K
Y
P
D
Y
E
S
K
G
I
K
A
Dog
Lupus familis
XP_536547
1100
121754
Y534
S
F
K
K
Y
P
D
Y
E
S
K
G
I
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
Y534
S
F
K
K
Y
P
D
Y
E
S
K
G
I
K
A
Rat
Rattus norvegicus
Q63617
999
111271
Y534
S
F
K
K
Y
P
D
Y
E
S
K
G
I
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
Y526
S
F
K
K
H
S
D
Y
E
S
K
G
I
K
A
Frog
Xenopus laevis
Q566I3
646
72655
R252
T
Q
P
Q
L
Q
I
R
G
V
G
F
D
R
T
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
A524
S
F
K
K
H
S
D
A
E
S
K
G
I
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
Y247
A
E
E
F
K
R
K
Y
K
K
D
L
R
S
N
Honey Bee
Apis mellifera
XP_624153
932
105575
A519
D
K
H
L
K
D
G
A
E
S
K
G
I
K
A
Nematode Worm
Caenorhab. elegans
P09446
640
69704
F246
V
N
H
F
C
A
E
F
K
R
K
H
K
K
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
S475
L
P
S
K
M
F
R
S
I
I
H
T
K
D
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
F469
K
K
L
P
S
K
M
F
R
S
F
V
L
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
A313
A
M
V
E
P
L
L
A
K
V
H
V
P
L
E
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
80
N.A.
6.6
46.6
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
20
86.6
N.A.
26.6
46.6
33.3
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
6.6
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
8
0
22
0
0
0
0
0
0
58
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
50
0
0
0
8
0
8
15
8
% D
% Glu:
0
8
8
8
0
0
8
0
58
0
0
0
0
0
8
% E
% Phe:
0
50
0
15
0
8
0
15
0
0
8
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
8
58
0
0
0
% G
% His:
0
0
15
0
15
0
0
0
0
0
15
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
8
8
0
0
58
0
0
% I
% Lys:
8
15
50
58
15
8
8
0
22
8
65
0
15
65
8
% K
% Leu:
8
0
8
8
8
8
8
0
0
0
0
8
8
8
0
% L
% Met:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
8
8
8
36
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
8
8
8
0
0
8
8
0
% R
% Ser:
50
0
8
0
8
15
0
8
0
65
0
0
0
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% T
% Val:
8
0
8
0
0
0
0
0
0
15
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
36
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _