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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4B
All Species:
28.79
Human Site:
S392
Identified Species:
48.72
UniProt:
Q9Y4P1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P1
NP_037457.3
393
44309
S392
D
E
D
F
E
I
L
S
L
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001162556
306
34202
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
L396
L
E
E
D
F
E
I
L
S
V
_
_
_
_
_
Dog
Lupus familis
XP_851977
394
44349
S393
D
E
D
F
E
I
L
S
L
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE6
393
44357
S392
D
E
D
F
E
I
L
S
L
_
_
_
_
_
_
Rat
Rattus norvegicus
NP_001119770
406
45887
L404
L
E
E
D
F
E
I
L
S
V
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
T527
D
E
D
F
E
I
L
T
L
_
_
_
_
_
_
Chicken
Gallus gallus
Q6PZ02
393
44512
S392
D
E
D
F
E
I
L
S
L
_
_
_
_
_
_
Frog
Xenopus laevis
Q640G7
384
43139
S383
D
E
E
F
E
I
L
S
L
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
S393
D
E
E
F
E
I
L
S
L
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624577
382
43001
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
C419
K
D
D
F
D
D
F
C
L
R
A
L
K
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
S496
D
E
V
E
T
L
E
S
D
D
D
G
E
P
A
Conservation
Percent
Protein Identity:
100
74.8
52.5
94.1
N.A.
94.9
52.4
N.A.
65.1
86
73.7
72.8
N.A.
N.A.
49.1
N.A.
49.8
Protein Similarity:
100
75.5
72.6
96.1
N.A.
96.6
70.9
N.A.
70
92.3
87
83.2
N.A.
N.A.
64.8
N.A.
64.3
P-Site Identity:
100
0
10
100
N.A.
100
10
N.A.
88.8
100
88.8
88.8
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
0
30
100
N.A.
100
30
N.A.
100
100
100
100
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
23.5
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
38.3
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
58
8
43
15
8
8
0
0
8
8
8
0
0
0
0
% D
% Glu:
0
72
29
8
50
15
8
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
58
15
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
50
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
15
0
0
0
0
8
50
15
58
0
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
15
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
15
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
50
65
65
65
65
65
% _