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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4B
All Species:
22.73
Human Site:
Y108
Identified Species:
38.46
UniProt:
Q9Y4P1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P1
NP_037457.3
393
44309
Y108
R
K
R
Q
P
D
S
Y
F
S
V
L
N
A
F
Chimpanzee
Pan troglodytes
XP_001162556
306
34202
T25
L
G
R
D
W
R
W
T
Q
R
K
R
Q
P
D
Rhesus Macaque
Macaca mulatta
XP_001097251
398
45435
E110
K
Q
K
E
Q
P
K
E
Y
Q
R
I
L
Q
C
Dog
Lupus familis
XP_851977
394
44349
Y109
R
K
R
Q
P
D
S
Y
F
N
V
L
N
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGE6
393
44357
Y108
R
K
R
Q
P
D
S
Y
F
N
V
L
N
A
F
Rat
Rattus norvegicus
NP_001119770
406
45887
Y111
Q
K
E
Q
P
K
E
Y
Q
R
I
L
Q
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513122
528
59425
Y244
G
R
R
Q
T
D
N
Y
F
N
V
L
N
A
F
Chicken
Gallus gallus
Q6PZ02
393
44512
Y107
G
K
R
Q
T
D
N
Y
F
S
V
L
N
A
F
Frog
Xenopus laevis
Q640G7
384
43139
D99
V
G
R
D
W
R
W
D
K
Q
K
P
K
G
E
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
Y108
G
Q
R
Q
R
P
E
Y
V
S
I
L
N
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624577
382
43001
W95
I
L
H
L
G
R
D
W
Q
W
S
L
E
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198708
393
44309
D111
R
W
R
P
Q
E
Q
D
E
T
Y
L
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
D130
D
E
N
S
G
E
T
D
T
G
T
V
L
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
Q197
I
P
R
S
S
D
P
Q
A
S
S
A
L
S
F
Conservation
Percent
Protein Identity:
100
74.8
52.5
94.1
N.A.
94.9
52.4
N.A.
65.1
86
73.7
72.8
N.A.
N.A.
49.1
N.A.
49.8
Protein Similarity:
100
75.5
72.6
96.1
N.A.
96.6
70.9
N.A.
70
92.3
87
83.2
N.A.
N.A.
64.8
N.A.
64.3
P-Site Identity:
100
6.6
0
93.3
N.A.
93.3
40
N.A.
66.6
80
6.6
53.3
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
6.6
40
100
N.A.
100
53.3
N.A.
86.6
86.6
6.6
66.6
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
23.5
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
38.3
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
0
50
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
0
15
0
43
8
22
0
0
0
0
0
0
8
% D
% Glu:
0
8
8
8
0
15
15
8
8
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
36
0
0
0
0
0
58
% F
% Gly:
22
15
0
0
15
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
15
8
0
8
0
% I
% Lys:
8
36
8
0
0
8
8
0
8
0
15
0
15
0
0
% K
% Leu:
8
8
0
8
0
0
0
0
0
0
0
65
22
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
15
0
0
22
0
0
43
0
0
% N
% Pro:
0
8
0
8
29
15
8
0
0
0
0
8
0
8
0
% P
% Gln:
8
15
0
50
15
0
8
8
22
15
0
0
15
8
0
% Q
% Arg:
29
8
72
0
8
22
0
0
0
15
8
8
0
0
8
% R
% Ser:
0
0
0
15
8
0
22
0
0
29
15
0
0
8
0
% S
% Thr:
0
0
0
0
15
0
8
8
8
8
8
0
0
8
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
36
8
0
0
0
% V
% Trp:
0
8
0
0
15
0
15
8
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _