KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
26.97
Human Site:
S223
Identified Species:
45.64
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
S223
S
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
S223
S
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
S222
S
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Dog
Lupus familis
XP_849029
445
50001
S222
N
L
K
G
H
V
L
S
T
I
N
T
N
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
S219
N
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Rat
Rattus norvegicus
XP_001071365
442
49595
S219
N
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
E69
R
C
L
R
A
N
V
E
L
D
H
A
E
L
V
Frog
Xenopus laevis
NP_001080380
436
48287
N224
I
N
T
N
Q
M
N
N
A
Y
A
A
V
S
L
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
A217
D
L
K
G
E
V
L
A
T
I
N
T
N
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
T703
D
L
K
G
Q
I
L
T
T
I
E
L
H
L
G
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
Q227
D
L
R
G
Q
L
L
Q
S
I
D
A
K
V
S
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
A231
N
T
K
G
E
V
L
A
S
V
D
T
H
H
M
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
S218
T
Y
G
S
G
D
G
S
T
I
V
A
S
C
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
I221
S
C
S
E
G
T
D
I
V
L
W
H
G
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
0
6.6
80
N.A.
N.A.
46.6
33.3
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
20
26.6
93.3
N.A.
N.A.
66.6
60
86.6
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
15
8
0
8
29
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
22
0
0
0
0
8
8
0
0
8
15
0
0
0
0
% D
% Glu:
0
0
0
8
15
0
0
8
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
72
15
0
8
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
8
15
8
0
% H
% Ile:
8
0
0
0
0
8
0
8
0
72
0
0
0
0
0
% I
% Lys:
0
0
65
0
0
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
65
8
0
0
8
72
0
8
8
0
8
0
15
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
58
% M
% Asn:
29
8
0
8
0
8
8
8
0
0
50
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
58
0
0
8
0
0
0
0
0
50
0
% Q
% Arg:
8
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
29
0
8
8
0
0
0
50
15
0
0
0
8
8
15
% S
% Thr:
8
8
8
0
0
8
0
8
65
0
0
58
0
0
8
% T
% Val:
0
0
0
0
0
58
8
0
8
8
8
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _