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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL2 All Species: 42.12
Human Site: S296 Identified Species: 71.28
UniProt: Q9Y4P3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4P3 NP_036585.1 447 49798 S296 N D S R R M A S V S K D G T W
Chimpanzee Pan troglodytes XP_001145648 447 49818 S296 N D S R R M A S V S K D G T W
Rhesus Macaque Macaca mulatta XP_001112014 446 49783 S295 N D S R R M A S V S K D G T W
Dog Lupus familis XP_849029 445 50001 S295 N D S R R M A S V S K D G T W
Cat Felis silvestris
Mouse Mus musculus Q9R099 442 49565 S292 N D S R R M A S V S K D G T W
Rat Rattus norvegicus XP_001071365 442 49595 S292 N D S R R M A S V S K D G T W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233611 267 29869 I128 H K A P V I N I G V A E T G K
Frog Xenopus laevis NP_001080380 436 48287 T288 N D S R R M A T V S K D G T W
Zebra Danio Brachydanio rerio NP_997932 439 49017 T290 N D S R R M V T V S K D G T W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397436 924 105676 T776 A D S S N M A T V S K D G T Y
Nematode Worm Caenorhab. elegans NP_495877 451 50863 T300 N S S T R A V T V S R D G K W
Sea Urchin Strong. purpuratus XP_001189381 459 50699 T304 L D S S R M A T V S K D G T W
Poplar Tree Populus trichocarpa XP_002301292 438 47608 V278 D V K V W E I V Y S K D G S V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567150 430 46532 R281 G S V K E V S R V M Q L K G H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 90.5 N.A. 87 87.9 N.A. N.A. 39.3 64.2 61.2 N.A. N.A. 21.7 28.8 47.9
Protein Similarity: 100 99.7 98.4 94.8 N.A. 93.5 93.5 N.A. N.A. 49.4 79.8 76.7 N.A. N.A. 33.6 53.2 66.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 93.3 86.6 N.A. N.A. 66.6 53.3 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 26.6 100 93.3 N.A. N.A. 80 66.6 86.6
Percent
Protein Identity: 27.9 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 44.7 N.A. N.A. 46.3 N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 65 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 72 0 0 0 0 0 0 0 0 0 86 0 0 0 % D
% Glu: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 8 0 0 0 86 15 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % I
% Lys: 0 8 8 8 0 0 0 0 0 0 79 0 8 8 8 % K
% Leu: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 72 0 0 0 8 0 0 0 0 0 % M
% Asn: 65 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 58 72 0 0 8 0 0 8 0 0 0 0 % R
% Ser: 0 15 79 15 0 0 8 43 0 86 0 0 0 8 0 % S
% Thr: 0 0 0 8 0 0 0 36 0 0 0 0 8 72 0 % T
% Val: 0 8 8 8 8 8 15 8 86 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 72 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _