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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
9.39
Human Site:
S39
Identified Species:
15.9
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
S39
L
R
A
G
E
E
R
S
G
R
P
A
C
Q
K
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
S39
L
R
A
G
E
E
R
S
G
R
P
A
C
Q
K
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
G39
L
R
A
E
E
R
S
G
R
P
A
C
R
K
A
Dog
Lupus familis
XP_849029
445
50001
G39
L
R
A
E
E
E
T
G
R
Q
V
C
Q
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
S39
L
R
A
E
E
K
P
S
Q
P
V
C
Q
K
E
Rat
Rattus norvegicus
XP_001071365
442
49595
S39
L
R
A
E
E
K
P
S
Q
P
I
C
Q
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
Frog
Xenopus laevis
NP_001080380
436
48287
A41
Q
D
P
S
D
K
K
A
N
G
E
D
A
P
E
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
P39
S
E
Q
K
K
D
S
P
G
E
E
N
T
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
F507
V
G
G
I
K
E
P
F
D
R
M
K
V
T
K
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
E40
K
E
Q
Q
G
E
Q
E
E
V
D
V
V
M
D
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
R39
M
I
V
C
G
A
G
R
G
K
P
E
E
E
E
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
E39
S
E
I
G
S
I
S
E
P
G
L
H
P
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
E41
V
Q
S
M
A
K
A
E
P
Q
D
P
I
R
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
100
26.6
33.3
N.A.
33.3
33.3
N.A.
N.A.
0
0
13.3
N.A.
N.A.
20
6.6
13.3
P-Site Similarity:
100
100
33.3
46.6
N.A.
53.3
53.3
N.A.
N.A.
0
33.3
26.6
N.A.
N.A.
33.3
13.3
40
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
43
0
8
8
8
8
0
0
8
15
8
0
15
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
29
15
0
0
% C
% Asp:
0
8
0
0
8
8
0
0
8
0
15
8
0
8
8
% D
% Glu:
0
22
0
29
43
36
0
22
8
8
15
8
8
8
29
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
22
15
0
8
15
29
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
8
8
0
8
0
0
0
0
8
0
8
0
0
% I
% Lys:
8
0
0
8
15
29
8
0
0
8
0
8
0
29
29
% K
% Leu:
43
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% L
% Met:
8
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% N
% Pro:
0
0
8
0
0
0
22
8
15
22
22
8
8
8
0
% P
% Gln:
8
8
15
8
0
0
8
0
15
15
0
0
22
15
0
% Q
% Arg:
0
43
0
0
0
8
15
8
15
22
0
0
8
8
0
% R
% Ser:
15
0
8
8
8
0
22
29
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% T
% Val:
15
0
8
0
0
0
0
0
0
8
15
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _