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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
26.06
Human Site:
S420
Identified Species:
44.1
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
S420
Q
G
H
L
K
R
A
S
N
E
S
T
R
Q
R
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
C420
Q
G
H
L
K
R
A
C
H
E
S
T
R
Q
R
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
S419
Q
G
H
L
K
R
A
S
T
D
S
T
R
Q
R
Dog
Lupus familis
XP_849029
445
50001
S418
Q
G
L
L
K
R
A
S
N
E
S
T
R
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
S415
Q
S
L
L
K
R
A
S
S
E
S
T
R
Q
R
Rat
Rattus norvegicus
XP_001071365
442
49595
S415
Q
G
L
L
K
R
A
S
S
E
S
T
R
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
G241
M
P
D
E
A
L
E
G
S
L
E
E
F
Y
T
Frog
Xenopus laevis
NP_001080380
436
48287
T409
K
D
M
F
K
K
A
T
N
K
G
T
K
D
R
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
S411
Q
T
M
L
K
K
A
S
N
D
G
V
R
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
Q897
K
R
K
L
M
Q
K
Q
T
S
A
T
K
E
R
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
P424
V
K
L
N
R
E
L
P
E
I
T
Q
E
G
A
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
S425
E
A
K
L
K
K
T
S
S
G
A
M
K
E
R
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
A411
W
A
P
K
P
M
P
A
G
D
G
R
S
F
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
I400
I
S
W
A
P
K
A
I
T
V
G
E
R
H
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
86.6
86.6
93.3
N.A.
80
86.6
N.A.
N.A.
0
33.3
60
N.A.
N.A.
20
0
26.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
66.6
73.3
N.A.
N.A.
53.3
13.3
66.6
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
8
0
65
8
0
0
15
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
22
0
0
0
8
0
% D
% Glu:
8
0
0
8
0
8
8
0
8
36
8
15
8
15
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
0
36
0
0
0
0
0
8
8
8
29
0
0
8
0
% G
% His:
0
0
22
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
15
8
15
8
65
29
8
0
0
8
0
0
22
0
0
% K
% Leu:
0
0
29
65
0
8
8
0
0
8
0
0
0
0
0
% L
% Met:
8
0
15
0
8
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
29
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
15
0
8
8
0
0
0
0
0
0
0
% P
% Gln:
50
0
0
0
0
8
0
8
0
0
0
8
0
50
0
% Q
% Arg:
0
8
0
0
8
43
0
0
0
0
0
8
58
0
72
% R
% Ser:
0
15
0
0
0
0
0
50
29
8
43
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
8
8
22
0
8
58
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
8
% V
% Trp:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _