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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL2 All Species: 23.33
Human Site: S423 Identified Species: 39.49
UniProt: Q9Y4P3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4P3 NP_036585.1 447 49798 S423 L K R A S N E S T R Q R L Q Q
Chimpanzee Pan troglodytes XP_001145648 447 49818 S423 L K R A C H E S T R Q R L Q Q
Rhesus Macaque Macaca mulatta XP_001112014 446 49783 S422 L K R A S T D S T R Q R L Q Q
Dog Lupus familis XP_849029 445 50001 S421 L K R A S N E S T R Q R L Q Q
Cat Felis silvestris
Mouse Mus musculus Q9R099 442 49565 S418 L K R A S S E S T R Q R L Q Q
Rat Rattus norvegicus XP_001071365 442 49595 S418 L K R A S S E S T R Q R L Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233611 267 29869 E244 E A L E G S L E E F Y T F R E
Frog Xenopus laevis NP_001080380 436 48287 G412 F K K A T N K G T K D R L Q K
Zebra Danio Brachydanio rerio NP_997932 439 49017 G414 L K K A S N D G V R Q R L R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397436 924 105676 A900 L M Q K Q T S A T K E R L E K
Nematode Worm Caenorhab. elegans NP_495877 451 50863 T427 N R E L P E I T Q E G A R R R
Sea Urchin Strong. purpuratus XP_001189381 459 50699 A428 L K K T S S G A M K E R L N Y
Poplar Tree Populus trichocarpa XP_002301292 438 47608 G414 K P M P A G D G R S F V L A T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567150 430 46532 G403 A P K A I T V G E R H A M V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.4 90.5 N.A. 87 87.9 N.A. N.A. 39.3 64.2 61.2 N.A. N.A. 21.7 28.8 47.9
Protein Similarity: 100 99.7 98.4 94.8 N.A. 93.5 93.5 N.A. N.A. 49.4 79.8 76.7 N.A. N.A. 33.6 53.2 66.6
P-Site Identity: 100 86.6 86.6 100 N.A. 93.3 93.3 N.A. N.A. 0 46.6 66.6 N.A. N.A. 26.6 0 33.3
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 100 N.A. N.A. 20 80 86.6 N.A. N.A. 66.6 26.6 66.6
Percent
Protein Identity: 27.9 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 44.7 N.A. N.A. 46.3 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 65 8 0 0 15 0 0 0 15 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 22 0 0 0 8 0 0 0 0 % D
% Glu: 8 0 8 8 0 8 36 8 15 8 15 0 0 8 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 8 8 0 8 0 0 % F
% Gly: 0 0 0 0 8 8 8 29 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 8 65 29 8 0 0 8 0 0 22 0 0 0 0 15 % K
% Leu: 65 0 8 8 0 0 8 0 0 0 0 0 79 0 8 % L
% Met: 0 8 8 0 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 0 29 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 15 0 8 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 8 0 50 0 0 50 50 % Q
% Arg: 0 8 43 0 0 0 0 0 8 58 0 72 8 22 8 % R
% Ser: 0 0 0 0 50 29 8 43 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 8 8 22 0 8 58 0 0 8 0 0 8 % T
% Val: 0 0 0 0 0 0 8 0 8 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _