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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
23.57
Human Site:
S441
Identified Species:
39.89
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
S441
Q
A
Q
E
T
L
K
S
L
G
A
L
K
K
_
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
S441
Q
A
Q
E
T
L
K
S
L
G
A
L
K
K
_
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
S440
Q
A
Q
E
T
L
K
S
L
G
A
L
K
K
_
Dog
Lupus familis
XP_849029
445
50001
S439
Q
A
Q
E
A
L
R
S
L
G
A
L
K
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
S436
Q
A
Q
E
A
L
K
S
L
G
A
L
K
K
_
Rat
Rattus norvegicus
XP_001071365
442
49595
S436
Q
A
Q
E
A
L
K
S
L
G
A
L
K
K
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
Frog
Xenopus laevis
NP_001080380
436
48287
A430
D
A
Q
S
A
L
D
A
V
C
K
Q
R
N
_
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
T432
D
A
Q
S
A
L
D
T
V
L
N
A
A
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
I918
D
N
R
K
F
L
Q
I
M
G
E
K
C
P
_
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
L445
Q
I
D
E
A
Q
E
L
L
K
Q
F
E
K
_
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
A446
S
T
S
E
D
I
D
A
I
L
N
V
S
P
T
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
A432
D
K
K
V
K
L
W
A
A
P
P
L
K
I
_
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
L421
G
D
D
K
K
V
K
L
W
E
A
P
K
S
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
100
100
85.7
N.A.
92.8
92.8
N.A.
N.A.
0
21.4
26.6
N.A.
N.A.
14.2
28.5
6.6
P-Site Similarity:
100
100
100
92.8
N.A.
92.8
92.8
N.A.
N.A.
0
42.8
40
N.A.
N.A.
42.8
42.8
33.3
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
21.4
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
35.7
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
0
43
0
0
22
8
0
50
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
29
8
15
0
8
0
22
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
58
0
0
8
0
0
8
8
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
8
8
0
0
0
0
8
0
% I
% Lys:
0
8
8
15
15
0
43
0
0
8
8
8
58
58
0
% K
% Leu:
0
0
0
0
0
72
0
15
50
15
0
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
15
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
8
0
15
0
% P
% Gln:
50
0
58
0
0
8
8
0
0
0
8
8
0
0
8
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
8
0
8
15
0
0
0
43
0
0
0
0
8
8
0
% S
% Thr:
0
8
0
0
22
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
8
0
0
15
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
72
% _