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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
9.09
Human Site:
S56
Identified Species:
15.38
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
S56
G
F
P
P
D
K
S
S
G
S
K
K
Q
K
Q
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
S56
G
F
P
P
D
K
S
S
G
S
K
K
Q
K
Q
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
S55
G
F
P
P
D
K
S
S
G
S
K
K
Q
K
Q
Dog
Lupus familis
XP_849029
445
50001
L55
G
F
P
P
D
K
S
L
K
S
K
K
Q
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
K55
E
P
K
K
S
G
S
K
K
Q
K
Q
N
Q
R
Rat
Rattus norvegicus
XP_001071365
442
49595
K55
E
S
K
K
S
V
S
K
K
Q
K
Q
N
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
Frog
Xenopus laevis
NP_001080380
436
48287
L60
K
K
P
K
Q
Q
K
L
R
K
E
K
P
Q
Q
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
Q55
P
S
R
K
Q
K
Q
Q
Q
Q
Q
Q
R
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
M536
E
N
G
K
W
V
F
M
R
E
R
T
D
K
S
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
E57
T
E
T
I
I
S
E
E
P
V
K
K
N
K
H
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
Q62
T
K
E
K
K
S
N
Q
A
N
K
K
Q
T
K
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
Q56
K
P
P
K
P
T
H
Q
S
R
K
P
H
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
N59
N
H
P
A
P
K
K
N
H
P
K
S
Q
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
N.A.
0
20
6.6
N.A.
N.A.
6.6
20
20
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
33.3
N.A.
N.A.
0
40
33.3
N.A.
N.A.
13.3
20
40
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
29
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
22
8
8
0
0
0
8
8
0
8
8
0
0
0
0
% E
% Phe:
0
29
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
29
0
8
0
0
8
0
0
22
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
8
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
15
15
50
8
43
15
15
22
8
72
50
0
43
15
% K
% Leu:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
8
8
0
8
0
0
22
0
0
% N
% Pro:
8
15
50
29
15
0
0
0
8
8
0
8
8
8
0
% P
% Gln:
0
0
0
0
15
8
8
22
8
22
8
22
43
22
36
% Q
% Arg:
0
0
8
0
0
0
0
0
15
8
8
0
8
0
22
% R
% Ser:
0
15
0
0
15
15
43
22
8
29
0
8
0
8
15
% S
% Thr:
15
0
8
0
0
8
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _