KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL2
All Species:
13.33
Human Site:
Y174
Identified Species:
22.56
UniProt:
Q9Y4P3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4P3
NP_036585.1
447
49798
Y174
T
K
R
E
D
G
G
Y
T
F
T
A
T
P
E
Chimpanzee
Pan troglodytes
XP_001145648
447
49818
Y174
T
K
R
E
D
G
G
Y
T
F
T
A
T
P
E
Rhesus Macaque
Macaca mulatta
XP_001112014
446
49783
Y173
T
K
R
E
D
G
G
Y
T
F
T
A
T
P
E
Dog
Lupus familis
XP_849029
445
50001
Y173
T
K
R
E
D
G
G
Y
T
F
T
A
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R099
442
49565
T173
E
D
G
G
F
T
F
T
A
T
P
E
D
F
P
Rat
Rattus norvegicus
XP_001071365
442
49595
T173
E
D
G
G
F
T
F
T
A
T
P
E
D
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233611
267
29869
G25
W
E
H
Q
G
H
S
G
S
V
S
C
L
H
F
Frog
Xenopus laevis
NP_001080380
436
48287
R178
A
P
E
D
F
A
K
R
H
K
A
P
I
I
N
Zebra Danio
Brachydanio rerio
NP_997932
439
49017
A173
G
T
F
N
F
K
A
A
P
G
D
F
P
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397436
924
105676
L654
S
K
K
S
D
G
T
L
A
S
A
A
K
A
L
Nematode Worm
Caenorhab. elegans
NP_495877
451
50863
G175
V
K
K
T
E
G
S
G
S
H
H
F
V
H
I
Sea Urchin
Strong. purpuratus
XP_001189381
459
50699
A180
G
K
R
E
D
S
S
A
V
Q
V
T
P
V
L
Poplar Tree
Populus trichocarpa
XP_002301292
438
47608
A174
W
G
E
E
K
V
K
A
T
D
D
S
K
Q
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567150
430
46532
L177
D
Q
Q
G
K
L
P
L
P
S
I
K
W
D
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.4
90.5
N.A.
87
87.9
N.A.
N.A.
39.3
64.2
61.2
N.A.
N.A.
21.7
28.8
47.9
Protein Similarity:
100
99.7
98.4
94.8
N.A.
93.5
93.5
N.A.
N.A.
49.4
79.8
76.7
N.A.
N.A.
33.6
53.2
66.6
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
N.A.
26.6
13.3
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
0
0
N.A.
N.A.
26.6
6.6
6.6
N.A.
N.A.
40
33.3
26.6
Percent
Protein Identity:
27.9
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
44.7
N.A.
N.A.
46.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
8
22
22
0
15
36
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
15
0
8
43
0
0
0
0
8
15
0
15
8
0
% D
% Glu:
15
8
15
43
8
0
0
0
0
0
0
15
0
0
29
% E
% Phe:
0
0
8
0
29
0
15
0
0
29
0
15
0
15
8
% F
% Gly:
15
8
15
22
8
43
29
15
0
8
0
0
0
0
0
% G
% His:
0
0
8
0
0
8
0
0
8
8
8
0
0
15
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
8
% I
% Lys:
0
50
15
0
15
8
15
0
0
8
0
8
15
0
8
% K
% Leu:
0
0
0
0
0
8
0
15
0
0
0
0
8
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
8
0
0
0
0
8
0
15
0
15
8
15
29
15
% P
% Gln:
0
8
8
8
0
0
0
0
0
8
0
0
0
15
8
% Q
% Arg:
0
0
36
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
8
22
0
15
15
8
8
0
0
0
% S
% Thr:
29
8
0
8
0
15
8
15
36
15
29
8
22
0
0
% T
% Val:
8
0
0
0
0
8
0
0
8
8
8
0
8
8
0
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
29
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _