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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPI2 All Species: 1.52
Human Site: T150 Identified Species: 3.03
UniProt: Q9Y4P8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4P8 NP_001028690.1 454 49408 T150 R D M K V L H T I R E T P P N
Chimpanzee Pan troglodytes XP_001165276 446 48667 C146 P A N P T G L C A L S I N H S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850630 436 47691 L143 T P P N P A G L C A L S I H N
Cat Felis silvestris
Mouse Mus musculus Q80W47 445 48459 L143 T P P N P A G L C A L S I N N
Rat Rattus norvegicus Q6AY57 445 48501 L143 T P P N P A G L C A L S I N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512711 416 45669 T124 V L H T I R E T P P N P A G L
Chicken Gallus gallus Q5ZHN3 436 47757 L143 T P P N P A G L C A L S I N N
Frog Xenopus laevis Q7ZWU5 435 47675 L143 T P P N P S G L C S L S I N G
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 G52 E K H E F L E G G V G H V E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624581 392 43147 L100 Y S Y S N T I L A V K L N R A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781358 486 52131 V164 G S S Q I G E V Q I F D T V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q96U88 461 50001 Y163 S P S S D S C Y L V Y P R P N
Conservation
Percent
Protein Identity: 100 55 N.A. 91.8 N.A. 93.1 93.6 N.A. 86.5 91.1 85 26.8 N.A. N.A. 61.4 N.A. 63.7
Protein Similarity: 100 72.6 N.A. 93.8 N.A. 94.7 94.9 N.A. 88.5 93.1 90.3 40.5 N.A. N.A. 72 N.A. 73
P-Site Identity: 100 0 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6 6.6 0 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 6.6 N.A. 13.3 N.A. 13.3 13.3 N.A. 13.3 13.3 6.6 13.3 N.A. N.A. 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.4
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45.3
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 34 0 0 17 34 0 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 9 9 42 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 9 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 9 0 0 9 0 0 25 0 0 0 9 0 0 9 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 0 0 17 42 9 9 0 9 0 0 9 9 % G
% His: 0 0 17 0 0 0 9 0 0 0 0 9 0 17 0 % H
% Ile: 0 0 0 0 17 0 9 0 9 9 0 9 42 0 0 % I
% Lys: 0 9 0 9 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 0 9 0 0 0 17 9 50 9 9 42 9 0 0 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 9 42 9 0 0 0 0 0 9 0 17 34 59 % N
% Pro: 9 50 42 9 42 0 0 0 9 9 0 17 9 17 0 % P
% Gln: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 9 0 0 0 9 0 0 9 9 0 % R
% Ser: 9 17 17 17 0 17 0 0 0 9 9 42 0 0 9 % S
% Thr: 42 0 0 9 9 9 0 17 0 0 0 9 9 0 0 % T
% Val: 9 0 0 0 9 0 0 9 0 25 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 9 0 0 0 0 9 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _