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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WIPI2 All Species: 3.64
Human Site: T382 Identified Species: 7.27
UniProt: Q9Y4P8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4P8 NP_001028690.1 454 49408 T382 L D G S L E T T N E I L D S A
Chimpanzee Pan troglodytes XP_001165276 446 48667 R374 E N K E N D L R P S L P Q S Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850630 436 47691 N365 D G S M E T T N E I L D S A S
Cat Felis silvestris
Mouse Mus musculus Q80W47 445 48459 H373 E I V D S A S H D C P L A T Q
Rat Rattus norvegicus Q6AY57 445 48501 H373 E I V D S A S H D C P L V T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512711 416 45669 D346 L M K Q H K L D G S M E P A N
Chicken Gallus gallus Q5ZHN3 436 47757 N365 D G S M E P A N E I L E S A S
Frog Xenopus laevis Q7ZWU5 435 47675 S365 D G S M E P S S E I L E S S S
Zebra Danio Brachydanio rerio Q7ZUW6 344 38148 S274 Q S S L A S A S F L P K Y F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624581 392 43147 V322 N V C A I T V V H K V L R L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781358 486 52131 T408 Y S P A P A K T F A S A T G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q96U88 461 50001 S391 A F I K I P K S S N N R A G G
Conservation
Percent
Protein Identity: 100 55 N.A. 91.8 N.A. 93.1 93.6 N.A. 86.5 91.1 85 26.8 N.A. N.A. 61.4 N.A. 63.7
Protein Similarity: 100 72.6 N.A. 93.8 N.A. 94.7 94.9 N.A. 88.5 93.1 90.3 40.5 N.A. N.A. 72 N.A. 73
P-Site Identity: 100 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6 0 6.6 0 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 26.6 N.A. 26.6 N.A. 26.6 26.6 N.A. 26.6 20 33.3 13.3 N.A. N.A. 40 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.4
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 45.3
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 17 9 25 17 0 0 9 0 9 17 25 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 25 9 0 17 0 9 0 9 17 0 0 9 9 0 0 % D
% Glu: 25 0 0 9 25 9 0 0 25 9 0 25 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 17 0 0 0 0 9 0 % F
% Gly: 0 25 9 0 0 0 0 0 9 0 0 0 0 17 17 % G
% His: 0 0 0 0 9 0 0 17 9 0 0 0 0 0 0 % H
% Ile: 0 17 9 0 17 0 0 0 0 25 9 0 0 0 0 % I
% Lys: 0 0 17 9 0 9 17 0 0 9 0 9 0 0 0 % K
% Leu: 17 0 0 9 9 0 17 0 0 9 34 34 0 9 9 % L
% Met: 0 9 0 25 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 9 0 0 9 0 0 17 9 9 9 0 0 0 9 % N
% Pro: 0 0 9 0 9 25 0 0 9 0 25 9 9 0 0 % P
% Gln: 9 0 0 9 0 0 0 0 0 0 0 0 9 0 17 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 9 9 0 0 % R
% Ser: 0 17 34 9 17 9 25 25 9 17 9 0 25 25 34 % S
% Thr: 0 0 0 0 0 17 17 17 0 0 0 0 9 17 0 % T
% Val: 0 9 17 0 0 0 9 9 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _