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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTLL3 All Species: 14.85
Human Site: S374 Identified Species: 40.83
UniProt: Q9Y4R7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4R7 NP_001021100.2 772 87414 S374 S L K N L D N S V H L C N N S
Chimpanzee Pan troglodytes XP_517039 903 101959 S415 S L K N L D N S V H L C N N S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541779 724 82364 P358 R N I W I V K P G A K S R G R
Cat Felis silvestris
Mouse Mus musculus A4Q9E5 927 104410 S567 S L K N L D N S V H L C N N S
Rat Rattus norvegicus Q641W7 461 53945 R103 V K N L K R F R K Q L E R E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1ECV4 771 88857 V399 D V R Q W F L V T D W N P L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM91 992 112237 S510 S L S N H H E S V H L T N Y A
Honey Bee Apis mellifera XP_393908 735 84876 K357 K L E D V M A K M N P S T K S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784103 1146 128055 S711 S L D D L A Q S I H L S N Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70 N.A. 75 N.A. 54.7 20.2 N.A. N.A. N.A. N.A. 43.2 N.A. 25.6 29.9 N.A. 28.7
Protein Similarity: 100 73.3 N.A. 79.1 N.A. 62.5 33.5 N.A. N.A. N.A. N.A. 60.7 N.A. 41.9 48.8 N.A. 42.1
P-Site Identity: 100 100 N.A. 0 N.A. 100 6.6 N.A. N.A. N.A. N.A. 0 N.A. 53.3 13.3 N.A. 53.3
P-Site Similarity: 100 100 N.A. 6.6 N.A. 100 13.3 N.A. N.A. N.A. N.A. 20 N.A. 60 46.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 12 0 0 12 0 0 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % C
% Asp: 12 0 12 23 0 34 0 0 0 12 0 0 0 0 0 % D
% Glu: 0 0 12 0 0 0 12 0 0 0 0 12 0 12 0 % E
% Phe: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 0 0 0 12 0 % G
% His: 0 0 0 0 12 12 0 0 0 56 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 12 12 34 0 12 0 12 12 12 0 12 0 0 12 0 % K
% Leu: 0 67 0 12 45 0 12 0 0 0 67 0 0 12 0 % L
% Met: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % M
% Asn: 0 12 12 45 0 0 34 0 0 12 0 12 56 34 0 % N
% Pro: 0 0 0 0 0 0 0 12 0 0 12 0 12 0 0 % P
% Gln: 0 0 0 12 0 0 12 0 0 12 0 0 0 12 0 % Q
% Arg: 12 0 12 0 0 12 0 12 0 0 0 0 23 0 12 % R
% Ser: 56 0 12 0 0 0 0 56 0 0 0 34 0 0 56 % S
% Thr: 0 0 0 0 0 0 0 0 12 0 0 12 12 0 12 % T
% Val: 12 12 0 0 12 12 0 12 45 0 0 0 0 0 0 % V
% Trp: 0 0 0 12 12 0 0 0 0 0 12 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _