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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL3
All Species:
7.58
Human Site:
S581
Identified Species:
20.83
UniProt:
Q9Y4R7
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4R7
NP_001021100.2
772
87414
S581
H
T
K
A
Q
L
P
S
P
H
V
L
R
H
Q
Chimpanzee
Pan troglodytes
XP_517039
903
101959
S719
H
T
K
A
Q
L
P
S
P
H
V
L
R
H
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541779
724
82364
A555
P
T
M
A
P
S
T
A
V
T
A
R
L
C
A
Cat
Felis silvestris
Mouse
Mus musculus
A4Q9E5
927
104410
K761
Q
Q
G
S
G
E
S
K
D
S
G
S
P
T
H
Rat
Rattus norvegicus
Q641W7
461
53945
W295
H
P
K
K
G
C
K
W
T
L
Q
R
F
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECV4
771
88857
K603
R
P
R
A
P
V
H
K
S
L
I
Q
S
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM91
992
112237
S749
S
S
R
S
S
L
C
S
Q
L
P
Q
K
S
P
Honey Bee
Apis mellifera
XP_393908
735
84876
Y566
T
G
E
F
E
L
A
Y
K
Q
R
M
S
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784103
1146
128055
A928
K
L
G
L
K
T
G
A
T
P
K
A
T
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70
N.A.
75
N.A.
54.7
20.2
N.A.
N.A.
N.A.
N.A.
43.2
N.A.
25.6
29.9
N.A.
28.7
Protein Similarity:
100
73.3
N.A.
79.1
N.A.
62.5
33.5
N.A.
N.A.
N.A.
N.A.
60.7
N.A.
41.9
48.8
N.A.
42.1
P-Site Identity:
100
100
N.A.
13.3
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
N.A.
20
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
40
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
0
0
12
23
0
0
12
12
0
0
12
% A
% Cys:
0
0
0
0
0
12
12
0
0
0
0
0
0
12
12
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
12
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
12
23
0
23
0
12
0
0
0
12
0
0
0
0
% G
% His:
34
0
0
0
0
0
12
0
0
23
0
0
0
34
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
12
0
34
12
12
0
12
23
12
0
12
0
12
0
0
% K
% Leu:
0
12
0
12
0
45
0
0
0
34
0
23
12
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
23
0
0
23
0
23
0
23
12
12
0
12
0
23
% P
% Gln:
12
12
0
0
23
0
0
0
12
12
12
23
0
0
34
% Q
% Arg:
12
0
23
0
0
0
0
0
0
0
12
23
23
12
0
% R
% Ser:
12
12
0
23
12
12
12
34
12
12
0
12
23
23
0
% S
% Thr:
12
34
0
0
0
12
12
0
23
12
0
0
12
23
0
% T
% Val:
0
0
0
0
0
12
0
0
12
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _