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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TELO2
All Species:
12.73
Human Site:
Y543
Identified Species:
25.45
UniProt:
Q9Y4R8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4R8
NP_057195.2
837
91747
Y543
R
A
L
E
G
L
V
Y
R
S
P
T
A
T
R
Chimpanzee
Pan troglodytes
XP_510730
670
73494
G404
E
E
K
T
C
V
V
G
F
A
G
L
R
Q
R
Rhesus Macaque
Macaca mulatta
XP_001089282
837
91724
Y543
R
A
L
E
G
L
V
Y
R
S
P
T
A
T
R
Dog
Lupus familis
XP_547196
826
89574
D542
K
A
P
A
Y
L
R
D
C
V
E
A
L
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC40
840
93294
Y544
K
G
L
E
G
L
V
Y
R
S
P
T
A
T
R
Rat
Rattus norvegicus
XP_220236
834
93042
Y544
K
V
L
E
G
L
V
Y
R
N
P
Q
A
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520471
540
60497
E274
L
T
T
S
E
D
M
E
R
W
E
A
A
L
R
Chicken
Gallus gallus
XP_415052
727
80265
L461
L
A
K
I
L
L
H
L
E
E
K
T
C
L
E
Frog
Xenopus laevis
Q6GPP1
835
93660
Q545
T
C
L
A
T
L
I
Q
A
N
T
S
A
T
K
Zebra Danio
Brachydanio rerio
Q7T006
822
91650
R536
Q
V
A
E
T
L
L
R
K
N
V
K
A
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793501
640
71866
E374
L
D
S
D
D
D
F
E
P
Y
D
M
S
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_680117
1017
113279
R651
Y
V
A
E
K
L
V
R
A
S
P
D
E
L
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
94
60.8
N.A.
74.7
75
N.A.
41.2
50.2
50.6
43.7
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
78.3
96.4
71.3
N.A.
83.3
83.7
N.A.
48.9
62.9
67.7
61.1
N.A.
N.A.
N.A.
N.A.
42.8
P-Site Identity:
100
13.3
100
20
N.A.
86.6
73.3
N.A.
20
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
26.6
N.A.
93.3
86.6
N.A.
26.6
20
53.3
60
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
17
17
0
0
0
0
17
9
0
17
59
0
0
% A
% Cys:
0
9
0
0
9
0
0
0
9
0
0
0
9
0
0
% C
% Asp:
0
9
0
9
9
17
0
9
0
0
9
9
0
0
9
% D
% Glu:
9
9
0
50
9
0
0
17
9
9
17
0
9
0
9
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
34
0
0
9
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
17
0
9
0
0
0
9
0
9
9
0
0
9
% K
% Leu:
25
0
42
0
9
75
9
9
0
0
0
9
9
25
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
9
0
42
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
9
0
0
0
9
0
9
9
% Q
% Arg:
17
0
0
0
0
0
9
17
42
0
0
0
9
0
50
% R
% Ser:
0
0
9
9
0
0
0
0
0
34
0
9
9
0
9
% S
% Thr:
9
9
9
9
17
0
0
0
0
0
9
34
0
59
9
% T
% Val:
0
25
0
0
0
9
50
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
9
0
0
0
9
0
0
34
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _