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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAS1L
All Species:
12.12
Human Site:
Y266
Identified Species:
38.1
UniProt:
Q9Y4W2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W2
NP_112483.1
734
83065
Y266
A
L
S
H
K
E
L
Y
E
R
A
R
E
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538062
772
88232
Y297
A
L
R
H
K
E
L
Y
E
R
A
R
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
A2BE28
776
89396
Y250
S
S
R
H
K
E
L
Y
E
K
A
R
E
L
L
Rat
Rattus norvegicus
NP_001164061
761
87418
Y250
S
P
R
H
K
E
L
Y
E
K
A
R
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516381
770
85455
V260
I
V
V
Q
L
K
N
V
V
Q
E
N
R
G
V
Chicken
Gallus gallus
XP_001231274
385
44410
Frog
Xenopus laevis
NP_001089301
946
108081
A431
S
T
A
N
Q
K
R
A
Q
D
A
S
L
N
V
Zebra Danio
Brachydanio rerio
NP_001119872
580
66287
D172
E
D
W
N
S
S
S
D
D
E
G
E
D
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.6
N.A.
67.7
65
N.A.
32
24.1
28.3
33.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
87.8
N.A.
79.2
77.9
N.A.
49.2
35.6
44.1
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
73.3
73.3
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
86.6
86.6
N.A.
26.6
0
53.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
13
0
0
0
0
13
0
0
63
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
13
13
13
0
0
13
13
0
% D
% Glu:
13
0
0
0
0
50
0
0
50
13
13
13
50
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
13
0
0
13
0
% G
% His:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
50
25
0
0
0
25
0
0
0
0
0
% K
% Leu:
0
25
0
0
13
0
50
0
0
0
0
0
13
50
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
0
13
0
0
0
0
13
0
13
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
13
0
0
0
13
13
0
0
0
0
0
% Q
% Arg:
0
0
38
0
0
0
13
0
0
25
0
50
13
0
0
% R
% Ser:
38
13
13
0
13
13
13
0
0
0
0
13
0
0
0
% S
% Thr:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
13
0
0
0
0
13
13
0
0
0
0
0
38
% V
% Trp:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _