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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFG3L2
All Species:
17.58
Human Site:
S50
Identified Species:
29.74
UniProt:
Q9Y4W6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W6
NP_006787.1
797
88584
S50
V
T
T
Q
A
R
A
S
R
N
S
L
L
T
D
Chimpanzee
Pan troglodytes
XP_512199
797
88551
S50
V
T
T
Q
A
R
A
S
R
N
S
L
L
T
D
Rhesus Macaque
Macaca mulatta
XP_001094146
798
88780
S50
V
T
T
Q
T
R
A
S
R
N
S
L
L
T
D
Dog
Lupus familis
XP_547682
806
89781
S51
A
T
T
Q
A
T
T
S
R
N
S
L
L
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ2
802
89500
S50
A
T
V
Q
T
A
S
S
R
R
S
L
L
R
D
Rat
Rattus norvegicus
Q7TT47
744
82104
P42
S
G
A
G
G
R
R
P
Y
V
V
R
G
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510851
790
87620
S40
A
V
V
C
L
R
G
S
R
I
E
Q
L
A
L
Chicken
Gallus gallus
XP_419121
806
89372
H51
V
P
T
G
V
T
T
H
R
R
T
V
L
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104667
800
88678
D41
G
V
G
Q
I
V
L
D
R
R
S
L
L
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730248
826
89682
E47
G
V
Y
I
L
P
T
E
L
S
P
L
L
R
Y
Honey Bee
Apis mellifera
XP_624548
803
91087
N40
L
S
L
I
R
N
G
N
E
T
S
T
M
E
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783782
792
87074
V38
L
H
S
T
N
A
D
V
T
T
S
W
K
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
Y21
S
R
S
K
G
F
V
Y
G
G
G
V
R
S
A
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
H28
R
S
Y
Y
G
L
T
H
I
K
S
L
H
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
94.2
N.A.
92.6
36.1
N.A.
72.7
80.8
N.A.
81
N.A.
60.6
61.3
N.A.
63.3
Protein Similarity:
100
100
99.1
95.9
N.A.
95.2
52.7
N.A.
82.4
87.7
N.A.
88.1
N.A.
73
75.2
N.A.
76.7
P-Site Identity:
100
100
93.3
80
N.A.
53.3
13.3
N.A.
26.6
26.6
N.A.
33.3
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
60
13.3
N.A.
26.6
40
N.A.
40
N.A.
20
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
0
22
15
22
0
0
0
0
0
0
15
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
36
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
8
15
22
0
15
0
8
8
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
15
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
15
8
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
15
0
8
0
15
8
8
0
8
0
0
58
65
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
8
0
29
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
8
0
8
0
0
8
0
0
0
8
% P
% Gln:
0
0
0
43
0
0
0
0
0
0
0
8
0
0
15
% Q
% Arg:
8
8
0
0
8
36
8
0
58
22
0
8
8
15
0
% R
% Ser:
15
15
15
0
0
0
8
43
0
8
65
0
0
15
15
% S
% Thr:
0
36
36
8
15
15
29
0
8
15
8
8
0
43
0
% T
% Val:
29
22
15
0
8
8
8
8
0
8
8
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
15
8
0
0
0
8
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _