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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AFG3L2 All Species: 33.33
Human Site: S656 Identified Species: 56.41
UniProt: Q9Y4W6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4W6 NP_006787.1 797 88584 S656 D L R K V T Q S A Y A Q I V Q
Chimpanzee Pan troglodytes XP_512199 797 88551 S656 D L R K V T Q S A Y A Q I V Q
Rhesus Macaque Macaca mulatta XP_001094146 798 88780 S657 D L R K V T Q S A Y A Q I V Q
Dog Lupus familis XP_547682 806 89781 S657 D L R K V T Q S A Y A Q I V Q
Cat Felis silvestris
Mouse Mus musculus Q8JZQ2 802 89500 S655 D L R K V T Q S A Y A Q I V Q
Rat Rattus norvegicus Q7TT47 744 82104 I620 D L R K V T R I A Y S M V K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510851 790 87620 S641 D L R K V T Q S A Y A Q I V Q
Chicken Gallus gallus XP_419121 806 89372 S657 D L K K V T Q S A Y A Q I V Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001104667 800 88678 S651 D L K K V T Q S A Y A Q I V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730248 826 89682 I674 D L K K I T D I A Y S Q V V R
Honey Bee Apis mellifera XP_624548 803 91087 N647 D L Q K V T S N A Y A Q V I Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783782 792 87074 M649 D L K K V T Q M A Y A Q V V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZI8 813 89536 M675 D L E K V T K M T Y A Q V A V
Baker's Yeast Sacchar. cerevisiae P40341 825 93258 S695 D D F K K V T S M A T A M V T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 94.2 N.A. 92.6 36.1 N.A. 72.7 80.8 N.A. 81 N.A. 60.6 61.3 N.A. 63.3
Protein Similarity: 100 100 99.1 95.9 N.A. 95.2 52.7 N.A. 82.4 87.7 N.A. 88.1 N.A. 73 75.2 N.A. 76.7
P-Site Identity: 100 100 100 100 N.A. 100 60 N.A. 100 93.3 N.A. 93.3 N.A. 53.3 66.6 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 45.5 47 N.A.
Protein Similarity: N.A. N.A. N.A. 61 62.3 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 86 8 79 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 100 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 15 0 0 0 0 58 8 0 % I
% Lys: 0 0 29 100 8 0 8 0 0 0 0 0 0 8 0 % K
% Leu: 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 15 8 0 0 8 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 65 0 0 0 0 86 0 0 79 % Q
% Arg: 0 0 50 0 0 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 0 0 0 0 8 65 0 0 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 93 8 0 8 0 8 0 0 0 8 % T
% Val: 0 0 0 0 86 8 0 0 0 0 0 0 36 79 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _