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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AFG3L2 All Species: 18.79
Human Site: S87 Identified Species: 31.79
UniProt: Q9Y4W6 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4W6 NP_006787.1 797 88584 S87 G K N G K K A S E P K E V M G
Chimpanzee Pan troglodytes XP_512199 797 88551 S87 G K N G K K A S E P K E V M G
Rhesus Macaque Macaca mulatta XP_001094146 798 88780 S87 G K N G K E A S E P K E V M G
Dog Lupus familis XP_547682 806 89781 S88 G K N G K K A S Q P K E V T G
Cat Felis silvestris
Mouse Mus musculus Q8JZQ2 802 89500 S87 G K N G K K A S E P K E A V G
Rat Rattus norvegicus Q7TT47 744 82104 L79 F E G V S G L L L K R H I V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510851 790 87620 V77 F K R S G R N V D P E E S T P
Chicken Gallus gallus XP_419121 806 89372 K88 G K K P N G T K G S A G E T K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001104667 800 88678 N78 N K N G G P K N S E P T P S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730248 826 89682 P84 G G K S S G Q P K G S V G D K
Honey Bee Apis mellifera XP_624548 803 91087 T77 K K V S S K T T E K V A E K V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783782 792 87074 P75 G K Q A A K K P K V A K E A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZI8 813 89536 H58 G L G F L R R H F A S F A A R
Baker's Yeast Sacchar. cerevisiae P40341 825 93258 P65 A K L N K E I P T D E E V E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 94.2 N.A. 92.6 36.1 N.A. 72.7 80.8 N.A. 81 N.A. 60.6 61.3 N.A. 63.3
Protein Similarity: 100 100 99.1 95.9 N.A. 95.2 52.7 N.A. 82.4 87.7 N.A. 88.1 N.A. 73 75.2 N.A. 76.7
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 0 N.A. 20 13.3 N.A. 20 N.A. 6.6 20 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 26.6 N.A. 40 13.3 N.A. 26.6 N.A. 13.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 45.5 47 N.A.
Protein Similarity: N.A. N.A. N.A. 61 62.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 36 0 0 8 15 8 15 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 0 % D
% Glu: 0 8 0 0 0 15 0 0 36 8 15 50 22 8 0 % E
% Phe: 15 0 0 8 0 0 0 0 8 0 0 8 0 0 0 % F
% Gly: 65 8 15 43 15 22 0 0 8 8 0 8 8 0 36 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % I
% Lys: 8 79 15 0 43 43 15 8 15 15 36 8 0 8 15 % K
% Leu: 0 8 8 0 8 0 8 8 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 22 0 % M
% Asn: 8 0 43 8 8 0 8 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 8 0 8 0 22 0 43 8 0 8 0 15 % P
% Gln: 0 0 8 0 0 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 15 8 0 0 0 8 0 0 0 8 % R
% Ser: 0 0 0 22 22 0 0 36 8 8 15 0 8 8 8 % S
% Thr: 0 0 0 0 0 0 15 8 8 0 0 8 0 22 0 % T
% Val: 0 0 8 8 0 0 0 8 0 8 8 8 36 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _