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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFG3L2
All Species:
14.55
Human Site:
T104
Identified Species:
24.62
UniProt:
Q9Y4W6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W6
NP_006787.1
797
88584
T104
K
E
S
K
P
A
A
T
T
R
S
S
G
G
G
Chimpanzee
Pan troglodytes
XP_512199
797
88551
T104
K
E
S
K
P
A
A
T
T
R
S
S
G
G
G
Rhesus Macaque
Macaca mulatta
XP_001094146
798
88780
T104
K
E
S
K
P
A
A
T
T
R
S
S
G
G
G
Dog
Lupus familis
XP_547682
806
89781
T105
K
E
S
K
P
A
A
T
P
S
P
S
G
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ2
802
89500
P104
K
E
P
Q
P
S
G
P
Q
P
S
G
G
A
G
Rat
Rattus norvegicus
Q7TT47
744
82104
G96
I
R
L
W
Q
L
S
G
S
T
L
Y
F
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510851
790
87620
E94
K
D
T
G
E
P
K
E
P
E
S
G
G
N
G
Chicken
Gallus gallus
XP_419121
806
89372
P105
K
Q
A
A
A
R
Q
P
S
G
T
G
S
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104667
800
88678
N95
V
K
E
A
K
P
T
N
S
Q
K
T
T
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730248
826
89682
A101
P
A
G
S
S
K
S
A
S
E
K
P
S
T
S
Honey Bee
Apis mellifera
XP_624548
803
91087
E94
A
S
S
K
E
T
S
E
S
Q
S
S
R
M
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783782
792
87074
S92
S
K
S
A
P
K
R
S
S
G
N
G
K
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
R75
L
E
A
G
D
L
S
R
A
F
A
N
P
R
L
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
E82
K
Q
V
E
K
Y
I
E
Q
T
K
N
N
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
94.2
N.A.
92.6
36.1
N.A.
72.7
80.8
N.A.
81
N.A.
60.6
61.3
N.A.
63.3
Protein Similarity:
100
100
99.1
95.9
N.A.
95.2
52.7
N.A.
82.4
87.7
N.A.
88.1
N.A.
73
75.2
N.A.
76.7
P-Site Identity:
100
100
100
80
N.A.
40
0
N.A.
26.6
20
N.A.
13.3
N.A.
0
26.6
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
53.3
13.3
N.A.
40
46.6
N.A.
40
N.A.
13.3
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
22
8
29
29
8
8
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
43
8
8
15
0
0
22
0
15
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
8
15
0
0
8
8
0
15
0
29
43
43
58
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
58
15
0
36
15
15
8
0
0
0
22
0
8
8
0
% K
% Leu:
8
0
8
0
0
15
0
0
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
15
8
15
0
% N
% Pro:
8
0
8
0
43
15
0
15
15
8
8
8
8
0
0
% P
% Gln:
0
15
0
8
8
0
8
0
15
15
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
8
0
22
0
0
8
8
0
% R
% Ser:
8
8
43
8
8
8
29
8
43
8
43
36
15
0
8
% S
% Thr:
0
0
8
0
0
8
8
29
22
15
8
8
8
15
8
% T
% Val:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _