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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFG3L2
All Species:
51.52
Human Site:
T221
Identified Species:
87.18
UniProt:
Q9Y4W6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W6
NP_006787.1
797
88584
T221
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Chimpanzee
Pan troglodytes
XP_512199
797
88551
T221
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Rhesus Macaque
Macaca mulatta
XP_001094146
798
88780
T222
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Dog
Lupus familis
XP_547682
806
89781
T222
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ2
802
89500
T220
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Rat
Rattus norvegicus
Q7TT47
744
82104
K221
M
Q
V
A
N
I
D
K
F
E
E
K
L
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510851
790
87620
T207
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Chicken
Gallus gallus
XP_419121
806
89372
T222
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104667
800
88678
T216
F
N
I
G
S
V
D
T
F
E
R
N
L
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730248
826
89682
S238
F
N
I
G
S
V
D
S
F
E
R
N
L
E
A
Honey Bee
Apis mellifera
XP_624548
803
91087
T214
F
N
I
G
S
V
E
T
F
E
R
N
L
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783782
792
87074
T216
F
N
I
G
S
V
D
T
F
E
R
N
L
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
S233
F
N
I
G
S
V
E
S
F
E
E
K
L
E
E
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
S261
F
T
I
G
S
I
D
S
F
E
H
K
L
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
94.2
N.A.
92.6
36.1
N.A.
72.7
80.8
N.A.
81
N.A.
60.6
61.3
N.A.
63.3
Protein Similarity:
100
100
99.1
95.9
N.A.
95.2
52.7
N.A.
82.4
87.7
N.A.
88.1
N.A.
73
75.2
N.A.
76.7
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
86
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
15
0
0
100
15
0
0
86
8
% E
% Phe:
93
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
93
0
0
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
22
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
86
0
0
8
0
0
0
0
0
0
79
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
79
0
0
8
0
% R
% Ser:
0
0
0
0
93
0
0
22
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
72
0
0
0
0
0
0
58
% T
% Val:
0
0
8
0
0
86
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _