KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AFG3L2
All Species:
20.91
Human Site:
Y62
Identified Species:
35.38
UniProt:
Q9Y4W6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4W6
NP_006787.1
797
88584
Y62
L
T
D
I
I
A
A
Y
Q
R
F
C
S
R
P
Chimpanzee
Pan troglodytes
XP_512199
797
88551
Y62
L
T
D
V
I
A
A
Y
Q
R
F
C
S
R
P
Rhesus Macaque
Macaca mulatta
XP_001094146
798
88780
Y62
L
T
D
V
I
A
A
Y
Q
R
F
C
S
R
P
Dog
Lupus familis
XP_547682
806
89781
Y63
L
T
D
V
I
A
A
Y
Q
R
F
C
S
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZQ2
802
89500
Y62
L
R
D
V
I
A
A
Y
Q
R
F
C
S
R
P
Rat
Rattus norvegicus
Q7TT47
744
82104
A54
G
T
P
I
G
L
A
A
A
G
G
H
T
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510851
790
87620
L52
L
A
L
Q
G
R
L
L
A
A
S
H
R
L
V
Chicken
Gallus gallus
XP_419121
806
89372
C63
L
A
S
V
I
A
A
C
R
R
L
F
S
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001104667
800
88678
Y53
L
S
Q
V
L
G
T
Y
R
R
L
S
S
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730248
826
89682
I59
L
R
Y
V
V
K
Q
I
Q
L
L
C
K
K
P
Honey Bee
Apis mellifera
XP_624548
803
91087
W52
M
E
H
I
R
N
Q
W
R
L
L
C
N
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783782
792
87074
R50
K
L
S
S
L
I
T
R
L
R
L
A
A
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZI8
813
89536
G33
R
S
A
V
F
N
Q
G
R
L
R
A
P
Q
N
Baker's Yeast
Sacchar. cerevisiae
P40341
825
93258
N40
H
T
Q
Y
R
L
L
N
R
L
Q
E
N
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
94.2
N.A.
92.6
36.1
N.A.
72.7
80.8
N.A.
81
N.A.
60.6
61.3
N.A.
63.3
Protein Similarity:
100
100
99.1
95.9
N.A.
95.2
52.7
N.A.
82.4
87.7
N.A.
88.1
N.A.
73
75.2
N.A.
76.7
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
20
N.A.
6.6
46.6
N.A.
33.3
N.A.
26.6
20
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
6.6
66.6
N.A.
66.6
N.A.
46.6
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
0
43
50
8
15
8
0
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
50
0
0
0
% C
% Asp:
0
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
36
8
0
0
0
% F
% Gly:
8
0
0
0
15
8
0
8
0
8
8
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
22
43
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
0
0
8
29
0
% K
% Leu:
65
8
8
0
15
15
15
8
8
29
36
0
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
15
0
8
0
0
0
0
15
0
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
72
% P
% Gln:
0
0
15
8
0
0
22
0
43
0
8
0
0
15
8
% Q
% Arg:
8
15
0
0
15
8
0
8
36
58
8
0
8
36
0
% R
% Ser:
0
15
15
8
0
0
0
0
0
0
8
8
50
0
8
% S
% Thr:
0
43
0
0
0
0
15
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
58
8
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _