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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLF12 All Species: 13.64
Human Site: S276 Identified Species: 37.5
UniProt: Q9Y4X4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4X4 NP_009180.3 402 44240 S276 E V H P S P V S R V R G N R M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001084640 398 43726 S272 E V H P S P V S R V R G N R M
Dog Lupus familis XP_542612 398 43730 S272 E V H P S P V S R V R G N R M
Cat Felis silvestris
Mouse Mus musculus O35738 402 44196 S276 E V H P S P V S R V R G N R M
Rat Rattus norvegicus O35819 283 31823 G165 S S Q L W G C G P G D L P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505429 456 49111 H330 S M S P M E I H S D S E D S V
Chicken Gallus gallus Q90WR8 771 80932 A522 T V N S I D S A G I Q L H Q G
Frog Xenopus laevis NP_001082615 357 38642 E239 D S D D S I V E T S S S F P D
Zebra Danio Brachydanio rerio NP_001103335 341 37326 I223 T G S T A L S I A R A V Q D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99 98 N.A. 96 31.3 N.A. 31.7 20.8 44 67.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99 98.2 N.A. 97.2 45 N.A. 47.3 32.4 58.9 73.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 0 N.A. 6.6 6.6 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 0 N.A. 33.3 46.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 12 12 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 12 12 0 12 0 0 0 12 12 0 12 12 12 % D
% Glu: 45 0 0 0 0 12 0 12 0 0 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % F
% Gly: 0 12 0 0 0 12 0 12 12 12 0 45 0 0 12 % G
% His: 0 0 45 0 0 0 0 12 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 12 12 12 12 0 12 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 12 0 0 0 0 0 23 0 0 0 % L
% Met: 0 12 0 0 12 0 0 0 0 0 0 0 0 0 45 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 45 0 0 % N
% Pro: 0 0 0 56 0 45 0 0 12 0 0 0 12 12 12 % P
% Gln: 0 0 12 0 0 0 0 0 0 0 12 0 12 12 0 % Q
% Arg: 0 0 0 0 0 0 0 0 45 12 45 0 0 45 0 % R
% Ser: 23 23 23 12 56 0 23 45 12 12 23 12 0 23 12 % S
% Thr: 23 0 0 12 0 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 56 0 0 0 0 56 0 0 45 0 12 0 0 12 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _