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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3H All Species: 24.85
Human Site: S161 Identified Species: 60.74
UniProt: Q9Y535 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y535 NP_001018060.1 204 22918 S161 D E S F V D T S P T G P S S A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105258 204 22959 S161 D E S F V D T S P T G P S S A
Dog Lupus familis XP_849136 204 22961 S161 D E S F V D T S P T G P S S A
Cat Felis silvestris
Mouse Mus musculus Q9D2C6 204 22929 S161 D E S F V D T S P T G P S S A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416229 206 23284 S161 D E T F V D T S P T G P S S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002476 214 23762 S161 D E V F V D T S P S G P S A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394665 203 22969 E160 V V S E T F T E A L P T G P N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796543 203 22989 T161 D E V F T D T T P V G P E D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38421 176 19443 V134 Y T T S D G S V K I Q K E C E
Baker's Yeast Sacchar. cerevisiae P35718 212 24307 K159 R E V F V D V K P K S P K E R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 96.5 N.A. 98 N.A. N.A. N.A. 88.3 N.A. 79.4 N.A. N.A. 64.2 N.A. 70.1
Protein Similarity: 100 N.A. 99.5 99.5 N.A. 99 N.A. N.A. N.A. 96.1 N.A. 88.3 N.A. N.A. 80.8 N.A. 82.3
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 93.3 N.A. 73.3 N.A. N.A. 13.3 N.A. 53.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 100 N.A. 86.6 N.A. N.A. 13.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 20.1 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 58.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 70 0 0 0 10 80 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 80 0 10 0 0 0 10 0 0 0 0 20 10 10 % E
% Phe: 0 0 0 80 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 70 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 10 10 0 10 10 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 80 0 10 80 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 0 0 50 10 0 0 10 60 0 10 10 0 60 50 0 % S
% Thr: 0 10 20 0 20 0 80 10 0 50 0 10 0 0 0 % T
% Val: 10 10 30 0 70 0 10 10 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _