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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3H
All Species:
13.94
Human Site:
S174
Identified Species:
34.07
UniProt:
Q9Y535
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y535
NP_001018060.1
204
22918
S174
S
A
D
A
T
T
S
S
E
E
L
P
K
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105258
204
22959
S174
S
A
D
A
T
T
S
S
E
E
L
P
K
K
E
Dog
Lupus familis
XP_849136
204
22961
S174
S
A
E
A
T
S
S
S
E
E
L
P
K
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2C6
204
22929
S174
S
A
E
A
A
S
S
S
E
E
L
P
K
K
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416229
206
23284
N174
S
A
E
A
S
T
S
N
A
T
E
E
V
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002476
214
23762
T174
A
D
K
E
A
P
G
T
G
A
A
A
A
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394665
203
22969
E173
P
N
I
S
G
E
T
E
T
S
E
A
K
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796543
203
22989
E174
D
G
L
E
A
G
A
E
E
N
E
T
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38421
176
19443
I147
C
E
V
R
L
K
I
I
G
T
R
V
D
A
T
Baker's Yeast
Sacchar. cerevisiae
P35718
212
24307
A172
E
R
E
L
E
E
R
A
Q
L
E
N
E
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
96.5
N.A.
98
N.A.
N.A.
N.A.
88.3
N.A.
79.4
N.A.
N.A.
64.2
N.A.
70.1
Protein Similarity:
100
N.A.
99.5
99.5
N.A.
99
N.A.
N.A.
N.A.
96.1
N.A.
88.3
N.A.
N.A.
80.8
N.A.
82.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
N.A.
N.A.
N.A.
33.3
N.A.
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
N.A.
66.6
N.A.
13.3
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
58.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
50
0
50
30
0
10
10
10
10
10
20
10
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
20
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
10
40
20
10
20
0
20
50
40
40
10
10
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
10
10
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
10
0
0
0
0
0
10
10
% I
% Lys:
0
0
10
0
0
10
0
0
0
0
0
0
60
50
10
% K
% Leu:
0
0
10
10
10
0
0
0
0
10
40
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
10
0
10
0
10
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
40
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
10
0
10
0
0
10
0
0
0
10
0
0
0
0
% R
% Ser:
50
0
0
10
10
20
50
40
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
30
30
10
10
10
20
0
10
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _