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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3H All Species: 12.42
Human Site: T171 Identified Species: 30.37
UniProt: Q9Y535 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y535 NP_001018060.1 204 22918 T171 G P S S A D A T T S S E E L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105258 204 22959 T171 G P S S A D A T T S S E E L P
Dog Lupus familis XP_849136 204 22961 T171 G P S S A E A T S S S E E L P
Cat Felis silvestris
Mouse Mus musculus Q9D2C6 204 22929 A171 G P S S A E A A S S S E E L P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416229 206 23284 S171 G P S S A E A S T S N A T E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002476 214 23762 A171 G P S A D K E A P G T G A A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394665 203 22969 G170 P T G P N I S G E T E T S E A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796543 203 22989 A171 G P E D G L E A G A E E N E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38421 176 19443 L144 Q K E C E V R L K I I G T R V
Baker's Yeast Sacchar. cerevisiae P35718 212 24307 E169 S P K E R E L E E R A Q L E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 96.5 N.A. 98 N.A. N.A. N.A. 88.3 N.A. 79.4 N.A. N.A. 64.2 N.A. 70.1
Protein Similarity: 100 N.A. 99.5 99.5 N.A. 99 N.A. N.A. N.A. 96.1 N.A. 88.3 N.A. N.A. 80.8 N.A. 82.3
P-Site Identity: 100 N.A. 100 86.6 N.A. 80 N.A. N.A. N.A. 53.3 N.A. 20 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. N.A. 73.3 N.A. 33.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20.1 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 58.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 50 0 50 30 0 10 10 10 10 10 20 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 20 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 20 10 10 40 20 10 20 0 20 50 40 40 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 70 0 10 0 10 0 0 10 10 10 0 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 10 10 0 0 10 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 10 10 0 0 0 0 10 40 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 0 10 0 10 % N
% Pro: 10 80 0 10 0 0 0 0 10 0 0 0 0 0 40 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 10 0 10 0 0 10 0 0 0 10 0 % R
% Ser: 10 0 60 50 0 0 10 10 20 50 40 0 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 30 30 10 10 10 20 0 10 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _