KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3H
All Species:
23.94
Human Site:
Y141
Identified Species:
58.52
UniProt:
Q9Y535
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y535
NP_001018060.1
204
22918
Y141
E
E
G
A
H
D
L
Y
M
D
T
G
E
E
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105258
204
22959
Y141
E
E
G
A
H
D
L
Y
M
D
T
G
E
E
I
Dog
Lupus familis
XP_849136
204
22961
Y141
E
E
G
A
H
D
L
Y
M
D
T
G
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2C6
204
22929
Y141
E
E
G
A
H
D
L
Y
M
D
T
G
E
E
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416229
206
23284
Y141
E
E
G
A
H
D
L
Y
M
D
I
G
E
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002476
214
23762
Y141
D
E
G
T
H
D
L
Y
M
D
Q
G
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394665
203
22969
D140
T
G
D
G
E
K
H
D
L
F
M
D
A
G
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796543
203
22989
F141
E
E
G
T
H
D
M
F
M
D
I
N
E
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38421
176
19443
P114
F
V
S
K
H
L
I
P
D
D
M
E
F
Q
A
Baker's Yeast
Sacchar. cerevisiae
P35718
212
24307
Y139
M
D
E
E
T
K
L
Y
F
D
V
N
E
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
96.5
N.A.
98
N.A.
N.A.
N.A.
88.3
N.A.
79.4
N.A.
N.A.
64.2
N.A.
70.1
Protein Similarity:
100
N.A.
99.5
99.5
N.A.
99
N.A.
N.A.
N.A.
96.1
N.A.
88.3
N.A.
N.A.
80.8
N.A.
82.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
80
N.A.
N.A.
0
N.A.
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
86.6
N.A.
N.A.
6.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
44.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
58.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
0
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
70
0
10
10
90
0
10
0
0
0
% D
% Glu:
60
70
10
10
10
0
0
0
0
0
0
10
80
70
10
% E
% Phe:
10
0
0
0
0
0
0
10
10
10
0
0
10
0
0
% F
% Gly:
0
10
70
10
0
0
0
0
0
0
0
60
0
10
0
% G
% His:
0
0
0
0
80
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
80
% I
% Lys:
0
0
0
10
0
20
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
10
70
0
10
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
10
0
70
0
20
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
20
10
0
0
0
0
0
40
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _