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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3H All Species: 27.27
Human Site: Y58 Identified Species: 66.67
UniProt: Q9Y535 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y535 NP_001018060.1 204 22918 Y58 I T K L E D A Y V F P G D G A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105258 204 22959 Y58 I T K L E D A Y V F P G D G A
Dog Lupus familis XP_849136 204 22961 Y58 I T R L E D A Y V F P G D G A
Cat Felis silvestris
Mouse Mus musculus Q9D2C6 204 22929 Y58 I T K L E D A Y V F P G D G A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416229 206 23284 Y58 I T K L E D S Y I F P G D G A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002476 214 23762 Y58 I T K L E D S Y I F P G D G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394665 203 22969 Y58 I T K I E E S Y I F P G D G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796543 203 22989 H58 I V K M E D S H I F P G D G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P38421 176 19443 F44 T C S G R H G F V V A I T G I
Baker's Yeast Sacchar. cerevisiae P35718 212 24307 Q58 L L T V E E G Q L K P G D G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 96.5 N.A. 98 N.A. N.A. N.A. 88.3 N.A. 79.4 N.A. N.A. 64.2 N.A. 70.1
Protein Similarity: 100 N.A. 99.5 99.5 N.A. 99 N.A. N.A. N.A. 96.1 N.A. 88.3 N.A. N.A. 80.8 N.A. 82.3
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 N.A. N.A. N.A. 86.6 N.A. 86.6 N.A. N.A. 73.3 N.A. 66.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 100 N.A. 100 N.A. N.A. 100 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 20.1 44.3 N.A.
Protein Similarity: N.A. N.A. N.A. 38.7 58.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 40 0 0 0 10 0 0 0 80 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 70 0 0 0 0 0 0 90 0 0 % D
% Glu: 0 0 0 0 90 20 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 80 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 20 0 0 0 0 90 0 100 0 % G
% His: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % H
% Ile: 80 0 0 10 0 0 0 0 40 0 0 10 0 0 10 % I
% Lys: 0 0 70 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 10 10 0 60 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 90 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 40 0 0 0 0 0 0 0 10 % S
% Thr: 10 70 10 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 10 0 10 0 0 0 0 50 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _