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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
28.48
Human Site:
S230
Identified Species:
41.78
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Chimpanzee
Pan troglodytes
XP_508638
381
41876
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Dog
Lupus familis
XP_850122
386
42276
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Rat
Rattus norvegicus
XP_341892
386
42298
S230
N
L
E
S
A
R
V
S
M
V
G
Q
V
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
G230
E
E
E
E
D
D
E
G
G
E
S
V
N
K
R
Chicken
Gallus gallus
NP_001026005
359
39669
V239
E
E
D
D
E
G
G
V
S
V
N
K
R
K
K
Frog
Xenopus laevis
NP_001086882
386
42454
A230
E
S
A
R
V
S
M
A
G
Q
I
K
Q
C
E
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
R200
D
I
P
R
S
T
A
R
R
L
A
E
D
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
I230
K
V
S
M
P
G
Q
I
I
N
C
T
T
N
K
Honey Bee
Apis mellifera
XP_623299
384
41915
A233
N
I
E
T
N
K
L
A
T
H
D
I
D
L
L
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
V238
R
N
P
T
A
A
R
V
S
M
P
S
Q
I
R
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
V236
P
S
V
S
I
T
D
V
I
T
E
E
E
E
S
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
S235
N
I
D
S
A
R
V
S
V
P
T
T
L
K
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
S315
N
S
T
S
A
R
T
S
V
P
G
L
L
A
P
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
13.3
0
0
N.A.
0
13.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
33.3
26.6
40
N.A.
20
46.6
26.6
26.6
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
57
7
7
13
0
0
7
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% C
% Asp:
7
0
13
7
7
7
7
0
0
0
7
0
13
0
0
% D
% Glu:
19
13
50
7
7
0
7
0
0
7
7
13
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
7
7
13
0
44
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
19
0
0
7
0
0
7
13
0
7
7
0
7
0
% I
% Lys:
7
0
0
0
0
7
0
0
0
0
0
13
0
57
13
% K
% Leu:
0
38
0
0
0
0
7
0
0
7
0
7
13
7
13
% L
% Met:
0
0
0
7
0
0
7
0
38
7
0
0
0
0
0
% M
% Asn:
57
7
0
0
7
0
0
0
0
7
7
0
7
7
0
% N
% Pro:
7
0
13
0
7
0
0
0
0
13
7
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
7
0
0
7
0
38
13
7
38
% Q
% Arg:
7
0
0
13
0
50
7
7
7
0
0
0
7
0
13
% R
% Ser:
0
19
7
57
7
7
0
50
13
0
7
7
0
0
7
% S
% Thr:
0
0
7
13
0
13
7
0
7
7
7
13
7
0
0
% T
% Val:
0
7
7
0
7
0
44
19
13
44
0
7
38
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _