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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
13.03
Human Site:
S269
Identified Species:
19.11
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
S269
E
E
G
S
E
S
I
S
K
R
K
K
E
D
D
Chimpanzee
Pan troglodytes
XP_508638
381
41876
S269
E
E
G
S
E
S
I
S
K
R
K
K
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
S269
E
E
G
S
E
S
I
S
K
R
K
K
E
D
D
Dog
Lupus familis
XP_850122
386
42276
N269
E
E
G
S
E
S
V
N
K
R
K
K
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
N269
E
E
G
S
E
S
V
N
K
R
K
K
E
D
D
Rat
Rattus norvegicus
XP_341892
386
42298
N269
E
E
G
S
E
S
V
N
K
R
K
K
E
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
S272
D
G
W
F
R
G
L
S
N
L
F
L
S
C
P
Chicken
Gallus gallus
NP_001026005
359
39669
S279
D
G
W
F
R
G
L
S
N
L
F
L
S
C
P
Frog
Xenopus laevis
NP_001086882
386
42454
N269
E
N
G
G
Q
S
I
N
K
R
K
K
E
D
D
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
E238
Y
G
W
R
I
N
L
E
S
I
S
N
H
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
F292
S
A
A
A
G
A
D
F
K
K
P
N
T
T
K
Honey Bee
Apis mellifera
XP_623299
384
41915
P271
E
P
V
N
M
P
P
P
S
T
P
T
G
T
T
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
L277
E
G
L
S
K
E
F
L
G
C
S
V
P
K
M
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
L275
P
Y
K
W
R
I
D
L
G
K
T
E
H
Y
W
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
L274
E
G
L
S
D
K
F
L
S
C
P
I
P
K
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
S369
E
D
W
F
V
G
L
S
K
K
F
L
E
A
R
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
6.6
6.6
73.3
0
N.A.
6.6
6.6
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
20
86.6
20
N.A.
26.6
13.3
20
13.3
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
0
7
0
0
0
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
13
0
% C
% Asp:
13
7
0
0
7
0
13
0
0
0
0
0
0
44
44
% D
% Glu:
69
38
0
0
38
7
0
7
0
0
0
7
50
0
7
% E
% Phe:
0
0
0
19
0
0
13
7
0
0
19
0
0
0
0
% F
% Gly:
0
32
44
7
7
19
0
0
13
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
7
7
25
0
0
7
0
7
0
0
0
% I
% Lys:
0
0
7
0
7
7
0
0
57
19
44
44
0
13
7
% K
% Leu:
0
0
13
0
0
0
25
19
0
13
0
19
0
7
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
7
0
7
0
25
13
0
0
13
0
0
0
% N
% Pro:
7
7
0
0
0
7
7
7
0
0
19
0
13
0
13
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
19
0
0
0
0
44
0
0
0
0
7
% R
% Ser:
7
0
0
50
0
44
0
38
19
0
13
0
13
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
7
7
7
7
13
7
% T
% Val:
0
0
7
0
7
0
19
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
25
7
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _