Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPME1 All Species: 29.39
Human Site: S27 Identified Species: 43.11
UniProt: Q9Y570 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y570 NP_057231.1 386 42315 S27 P G S G G S Q S G A K M R M G
Chimpanzee Pan troglodytes XP_508638 381 41876 S27 P G S G G S Q S G A K M R M G
Rhesus Macaque Macaca mulatta XP_001115651 405 44400 S27 P G S G G S Q S G A K M R M G
Dog Lupus familis XP_850122 386 42276 S27 P G S G G S Q S G A K M R M G
Cat Felis silvestris
Mouse Mus musculus Q8BVQ5 386 42238 S27 P G S G G S Q S G A K M R M G
Rat Rattus norvegicus XP_341892 386 42298 S27 P G S G G S Q S G A K M R M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517056 352 38800 E27 E D V V V E N E T G K D T F R
Chicken Gallus gallus NP_001026005 359 39669 T36 E N E T G K D T F R I Y K S G
Frog Xenopus laevis NP_001086882 386 42454 S27 P G G L Q S G S K M R M G P G
Zebra Danio Brachydanio rerio Q6DRD9 317 34905
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648277 409 45331 S27 G R I G R A D S F K K S R I R
Honey Bee Apis mellifera XP_623299 384 41915 K30 S S R I N K S K G F Q R K R D
Nematode Worm Caenorhab. elegans Q9BIB3 364 40203 H35 L L R Q A V T H G R P P P V P
Sea Urchin Strong. purpuratus XP_001202410 365 39617 L33 D S F E D V A L N S D D I F R
Poplar Tree Populus trichocarpa XP_002325511 354 39103 P32 N L K N P P V P A F S S V P T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGG8 454 48937 S112 K E E A G P D S G S R T S N K
Conservation
Percent
Protein Identity: 100 98.4 90.3 98.4 N.A. 97.9 97.9 N.A. 86.2 84.7 85.2 20.4 N.A. 47.4 52 42.4 59.5
Protein Similarity: 100 98.6 91.3 98.9 N.A. 99.4 99.4 N.A. 88.5 87.8 93 40.4 N.A. 67.2 70.9 58.8 72.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 13.3 40 0 N.A. 26.6 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 26.6 46.6 0 N.A. 40 20 13.3 6.6
Percent
Protein Identity: 43.5 N.A. N.A. N.A. N.A. 36.1
Protein Similarity: 60.3 N.A. N.A. N.A. N.A. 51.3
P-Site Identity: 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 0 N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 7 7 7 0 7 38 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 7 0 19 0 0 0 7 13 0 0 7 % D
% Glu: 13 7 13 7 0 7 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 13 13 0 0 0 13 0 % F
% Gly: 7 44 7 44 50 0 7 0 57 7 0 0 7 0 50 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 7 0 0 0 0 0 0 7 0 7 7 0 % I
% Lys: 7 0 7 0 0 13 0 7 7 7 50 0 13 0 7 % K
% Leu: 7 13 0 7 0 0 0 7 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 44 0 38 0 % M
% Asn: 7 7 0 7 7 0 7 0 7 0 0 0 0 7 0 % N
% Pro: 44 0 0 0 7 13 0 7 0 0 7 7 7 13 7 % P
% Gln: 0 0 0 7 7 0 38 0 0 0 7 0 0 0 0 % Q
% Arg: 0 7 13 0 7 0 0 0 0 13 13 7 44 7 19 % R
% Ser: 7 13 38 0 0 44 7 57 0 13 7 13 7 7 0 % S
% Thr: 0 0 0 7 0 0 7 7 7 0 0 7 7 0 7 % T
% Val: 0 0 7 7 7 13 7 0 0 0 0 0 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _