KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
24.85
Human Site:
S52
Identified Species:
36.44
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
S52
P
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Chimpanzee
Pan troglodytes
XP_508638
381
41876
S52
P
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
S52
P
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Dog
Lupus familis
XP_850122
386
42276
S52
S
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
S52
P
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Rat
Rattus norvegicus
XP_341892
386
42298
S52
P
W
S
Q
Y
F
E
S
M
E
D
V
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
G52
L
L
L
L
H
G
G
G
H
S
A
L
S
W
A
Chicken
Gallus gallus
NP_001026005
359
39669
S61
G
G
G
H
S
A
L
S
W
A
V
F
T
S
A
Frog
Xenopus laevis
NP_001086882
386
42454
E52
S
Q
Y
F
E
S
M
E
D
V
V
V
E
S
E
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
S22
R
G
A
P
C
G
L
S
S
C
S
S
V
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
T52
F
A
E
K
E
D
V
T
V
D
E
Q
R
T
F
Honey Bee
Apis mellifera
XP_623299
384
41915
I55
D
H
S
Q
D
V
K
I
G
D
D
I
F
H
I
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
D60
M
S
E
L
P
W
S
D
F
F
D
E
K
K
D
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
G58
V
F
F
L
H
G
G
G
H
S
A
L
S
W
A
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
E57
Y
V
P
L
E
W
T
E
F
F
D
K
E
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
K137
Y
L
T
S
P
V
G
K
G
P
L
F
V
T
H
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
0
6.6
20
6.6
N.A.
0
20
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
6.6
20
13.3
N.A.
33.3
40
26.6
20
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
7
0
0
0
7
13
0
0
0
19
% A
% Cys:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
7
0
7
7
13
57
0
0
0
13
% D
% Glu:
0
0
13
0
19
0
38
13
0
38
7
7
50
7
44
% E
% Phe:
7
7
7
7
0
38
0
0
13
13
0
13
7
0
7
% F
% Gly:
7
13
7
0
0
19
19
13
13
0
0
0
0
0
7
% G
% His:
0
7
0
7
13
0
0
0
13
0
0
0
0
7
7
% H
% Ile:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
7
% I
% Lys:
0
0
0
7
0
0
7
7
0
0
0
7
7
7
0
% K
% Leu:
7
13
7
25
0
0
13
0
0
0
7
13
0
0
0
% L
% Met:
7
0
0
0
0
0
7
0
38
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
32
0
7
7
13
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
7
0
44
0
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
13
7
44
7
7
7
7
50
7
13
7
7
13
13
0
% S
% Thr:
0
0
7
0
0
0
7
7
0
0
0
0
7
19
0
% T
% Val:
7
7
0
0
0
13
7
0
7
7
13
44
13
38
0
% V
% Trp:
0
38
0
0
0
13
0
0
7
0
0
0
0
13
0
% W
% Tyr:
13
0
7
0
38
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _