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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPME1 All Species: 26.62
Human Site: S7 Identified Species: 39.05
UniProt: Q9Y570 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y570 NP_057231.1 386 42315 S7 _ M S A L E K S M H L G R L P
Chimpanzee Pan troglodytes XP_508638 381 41876 S7 _ M S A L E K S M H L G R L P
Rhesus Macaque Macaca mulatta XP_001115651 405 44400 S7 _ M S A L E K S M H L G R L P
Dog Lupus familis XP_850122 386 42276 S7 _ M S A L E K S M H L G R L P
Cat Felis silvestris
Mouse Mus musculus Q8BVQ5 386 42238 S7 _ M S A L E K S M H L G R L P
Rat Rattus norvegicus XP_341892 386 42298 S7 _ M S A L E K S M H L G R L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517056 352 38800 F7 _ P G R K R D F S P V P W S Q
Chicken Gallus gallus NP_001026005 359 39669 W16 R D F S P V L W S Q Y F E S M
Frog Xenopus laevis NP_001086882 386 42454 H7 _ M S A L E K H L H M G G L P
Zebra Danio Brachydanio rerio Q6DRD9 317 34905
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648277 409 45331 T7 _ M S S L Q R T M L K G K L P
Honey Bee Apis mellifera XP_623299 384 41915 K10 S L Q K S I L K S K L P P S G
Nematode Worm Caenorhab. elegans Q9BIB3 364 40203 E15 T L P D L Q S E T S H V T T P
Sea Urchin Strong. purpuratus XP_001202410 365 39617 K13 P H G F G A R K R D F T P L P
Poplar Tree Populus trichocarpa XP_002325511 354 39103 E12 N L T S L P E E T L D V E D E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SGG8 454 48937 I92 A S R S M D P I P W T T Y F E
Conservation
Percent
Protein Identity: 100 98.4 90.3 98.4 N.A. 97.9 97.9 N.A. 86.2 84.7 85.2 20.4 N.A. 47.4 52 42.4 59.5
Protein Similarity: 100 98.6 91.3 98.9 N.A. 99.4 99.4 N.A. 88.5 87.8 93 40.4 N.A. 67.2 70.9 58.8 72.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 0 71.4 0 N.A. 50 6.6 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 7.1 6.6 85.7 0 N.A. 85.7 13.3 26.6 20
Percent
Protein Identity: 43.5 N.A. N.A. N.A. N.A. 36.1
Protein Similarity: 60.3 N.A. N.A. N.A. N.A. 51.3
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 44 0 7 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 7 7 0 0 7 7 0 0 7 0 % D
% Glu: 0 0 0 0 0 44 7 13 0 0 0 0 13 0 13 % E
% Phe: 0 0 7 7 0 0 0 7 0 0 7 7 0 7 0 % F
% Gly: 0 0 13 0 7 0 0 0 0 0 0 50 7 0 7 % G
% His: 0 7 0 0 0 0 0 7 0 44 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 7 0 44 13 0 7 7 0 7 0 0 % K
% Leu: 0 19 0 0 63 0 13 0 7 13 44 0 0 57 0 % L
% Met: 0 50 0 0 7 0 0 0 44 0 7 0 0 0 7 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 7 7 7 0 7 7 7 0 7 7 0 13 13 0 63 % P
% Gln: 0 0 7 0 0 13 0 0 0 7 0 0 0 0 7 % Q
% Arg: 7 0 7 7 0 7 13 0 7 0 0 0 38 0 0 % R
% Ser: 7 7 50 25 7 0 7 38 19 7 0 0 0 19 0 % S
% Thr: 7 0 7 0 0 0 0 7 13 0 7 13 7 7 0 % T
% Val: 0 0 0 0 0 7 0 0 0 0 7 13 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 7 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % Y
% Spaces: 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _