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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
27.27
Human Site:
T118
Identified Species:
40
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
T118
D
L
R
S
H
G
E
T
K
V
K
N
P
E
D
Chimpanzee
Pan troglodytes
XP_508638
381
41876
T118
D
L
R
S
H
G
E
T
K
V
K
N
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
T118
D
L
R
S
H
G
E
T
K
V
K
N
P
E
D
Dog
Lupus familis
XP_850122
386
42276
T118
D
L
R
G
H
G
E
T
K
V
K
N
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
T118
D
L
R
G
H
G
E
T
K
V
K
N
S
E
D
Rat
Rattus norvegicus
XP_341892
386
42298
T118
D
L
R
S
H
G
E
T
K
V
K
N
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
L118
D
L
P
P
P
I
M
L
I
G
H
S
M
G
G
Chicken
Gallus gallus
NP_001026005
359
39669
M127
I
M
L
I
G
H
S
M
G
G
A
I
A
V
H
Frog
Xenopus laevis
NP_001086882
386
42454
V118
R
G
H
G
E
T
K
V
R
N
P
E
E
L
S
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
K88
S
N
F
H
S
I
A
K
S
L
V
Q
R
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
E118
G
D
S
K
V
D
D
E
D
D
L
S
A
D
T
Honey Bee
Apis mellifera
XP_623299
384
41915
A121
S
N
E
E
D
L
S
A
D
T
L
A
K
D
V
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
T126
D
L
R
G
H
G
D
T
K
C
S
D
E
H
D
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
I124
G
D
D
G
Q
P
I
I
L
V
G
H
S
M
G
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
T123
D
L
R
G
H
G
K
T
S
T
E
N
E
L
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
P203
T
T
G
Q
A
P
P
P
L
D
L
S
L
S
T
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
13.3
0
0
0
N.A.
0
0
53.3
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
20
6.6
13.3
6.6
N.A.
20
6.6
66.6
13.3
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
7
0
0
7
7
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
57
13
7
0
7
7
13
0
13
13
0
7
0
13
50
% D
% Glu:
0
0
7
7
7
0
38
7
0
0
7
7
19
38
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
7
7
38
7
50
0
0
7
13
7
0
0
7
19
% G
% His:
0
0
7
7
50
7
0
0
0
0
7
7
0
7
7
% H
% Ile:
7
0
0
7
0
13
7
7
7
0
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
0
13
7
44
0
38
0
7
0
0
% K
% Leu:
0
57
7
0
0
7
0
7
13
7
19
0
7
13
0
% L
% Met:
0
7
0
0
0
0
7
7
0
0
0
0
7
7
0
% M
% Asn:
0
13
0
0
0
0
0
0
0
7
0
44
0
0
0
% N
% Pro:
0
0
7
7
7
13
7
7
0
0
7
0
19
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
50
0
0
0
0
0
7
0
0
0
7
0
0
% R
% Ser:
13
0
7
25
7
0
13
0
13
0
7
19
25
7
7
% S
% Thr:
7
7
0
0
0
7
0
50
0
13
0
0
0
7
13
% T
% Val:
0
0
0
0
7
0
0
7
0
44
7
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _