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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
31.82
Human Site:
T286
Identified Species:
46.67
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Chimpanzee
Pan troglodytes
XP_508638
381
41876
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Dog
Lupus familis
XP_850122
386
42276
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Rat
Rattus norvegicus
XP_341892
386
42298
T286
T
K
K
D
H
P
Y
T
W
R
I
E
L
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
V289
K
L
L
L
L
A
G
V
D
R
L
D
K
D
L
Chicken
Gallus gallus
NP_001026005
359
39669
V296
K
L
L
L
L
A
G
V
D
R
L
D
K
D
L
Frog
Xenopus laevis
NP_001086882
386
42454
T286
T
K
K
E
R
P
Y
T
W
R
I
E
L
S
K
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
T255
L
G
F
P
E
F
D
T
T
Y
E
G
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
T309
T
E
A
A
K
N
Y
T
W
R
I
D
L
S
K
Honey Bee
Apis mellifera
XP_623299
384
41915
D288
R
K
Y
V
W
R
I
D
L
S
K
T
E
Q
H
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
D294
L
A
G
V
D
R
L
D
R
D
L
T
I
G
Q
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
L292
W
F
K
G
M
S
N
L
F
L
S
C
N
V
P
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
D291
L
A
G
T
D
R
L
D
R
S
L
T
I
G
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
T386
K
M
L
L
L
A
G
T
D
R
L
D
T
E
L
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
6.6
80
6.6
N.A.
53.3
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
20
93.3
6.6
N.A.
73.3
6.6
20
13.3
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
7
7
0
19
0
0
0
0
0
0
0
38
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
38
13
0
7
19
19
7
0
25
0
13
0
% D
% Glu:
0
7
0
7
7
0
0
0
0
0
7
44
7
7
0
% E
% Phe:
0
7
7
0
0
7
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
7
13
7
0
0
19
0
0
0
0
7
0
13
0
% G
% His:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
50
0
13
0
0
% I
% Lys:
19
50
50
0
7
0
0
0
0
0
7
0
13
0
50
% K
% Leu:
19
13
19
19
19
0
13
7
7
7
32
0
50
0
25
% L
% Met:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
7
0
44
0
0
0
0
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% Q
% Arg:
7
0
0
0
7
19
0
0
13
69
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
0
13
7
0
0
13
0
% S
% Thr:
50
0
0
7
0
0
0
63
7
0
0
19
7
7
0
% T
% Val:
0
0
0
13
0
0
0
13
0
0
0
0
0
7
0
% V
% Trp:
7
0
0
0
7
0
0
0
50
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
50
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _