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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
37.27
Human Site:
T331
Identified Species:
54.67
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Chimpanzee
Pan troglodytes
XP_508638
381
41876
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Dog
Lupus familis
XP_850122
386
42276
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Rat
Rattus norvegicus
XP_341892
386
42298
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
A330
D
K
V
A
E
A
V
A
T
F
L
I
R
H
R
Chicken
Gallus gallus
NP_001026005
359
39669
A337
D
K
V
A
E
A
V
A
T
F
L
I
R
H
R
Frog
Xenopus laevis
NP_001086882
386
42454
T331
D
R
L
D
K
D
L
T
I
G
Q
M
Q
G
K
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
A295
D
I
Q
Y
I
P
D
A
S
H
W
I
H
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
T354
D
G
L
D
R
T
L
T
V
G
Q
M
Q
G
R
Honey Bee
Apis mellifera
XP_623299
384
41915
T329
D
R
L
D
R
E
L
T
V
G
Q
M
Q
G
K
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
C335
D
E
V
G
R
F
A
C
R
H
R
I
A
Q
P
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
G332
M
Q
V
L
P
Q
C
G
H
A
V
H
E
D
Q
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
S332
T
L
I
I
N
F
I
S
R
N
R
I
G
P
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
V427
E
K
T
A
I
A
L
V
D
F
H
R
R
N
D
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
6.6
100
6.6
N.A.
66.6
80
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
53.3
53.3
100
13.3
N.A.
86.6
100
33.3
26.6
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
19
7
19
0
7
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% C
% Asp:
82
0
0
57
0
44
7
0
7
0
0
0
0
7
13
% D
% Glu:
7
7
0
0
13
7
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
19
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
0
0
7
0
57
0
0
7
57
0
% G
% His:
0
0
0
0
0
0
0
0
7
13
7
7
7
13
7
% H
% Ile:
0
7
7
7
13
0
7
0
44
0
0
32
0
0
0
% I
% Lys:
0
19
0
0
44
0
0
0
0
0
0
0
0
0
50
% K
% Leu:
0
7
57
7
0
0
63
0
0
0
13
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
57
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
7
7
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
7
7
0
0
7
0
0
0
0
57
0
57
7
7
% Q
% Arg:
0
50
0
0
19
0
0
0
13
0
13
7
19
0
19
% R
% Ser:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% S
% Thr:
7
0
7
0
0
7
0
57
13
0
0
0
0
0
0
% T
% Val:
0
0
25
0
0
0
13
7
13
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _