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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPME1
All Species:
23.64
Human Site:
T66
Identified Species:
34.67
UniProt:
Q9Y570
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y570
NP_057231.1
386
42315
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Chimpanzee
Pan troglodytes
XP_508638
381
41876
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Rhesus Macaque
Macaca mulatta
XP_001115651
405
44400
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Dog
Lupus familis
XP_850122
386
42276
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVQ5
386
42238
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Rat
Rattus norvegicus
XP_341892
386
42298
T66
E
N
E
T
G
K
D
T
F
R
V
Y
K
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517056
352
38800
I66
A
V
F
T
V
A
I
I
S
R
I
Q
C
R
I
Chicken
Gallus gallus
NP_001026005
359
39669
C75
A
I
I
S
R
I
Q
C
R
I
V
A
L
D
L
Frog
Xenopus laevis
NP_001086882
386
42454
R66
E
T
G
K
A
S
F
R
V
Y
R
S
G
S
E
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
G36
G
L
R
D
F
C
S
G
V
S
R
L
D
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648277
409
45331
Q66
F
R
I
Y
R
T
K
Q
P
E
K
P
G
P
V
Honey Bee
Apis mellifera
XP_623299
384
41915
G69
I
Y
T
K
G
T
D
G
P
T
L
V
L
L
H
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
V74
D
A
N
I
D
G
D
V
F
N
V
Y
I
K
G
Sea Urchin
Strong. purpuratus
XP_001202410
365
39617
S72
A
L
L
A
Q
Q
L
S
G
M
V
K
C
R
V
Poplar Tree
Populus trichocarpa
XP_002325511
354
39103
D71
D
V
C
I
P
D
S
D
D
V
F
H
V
Y
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGG8
454
48937
G151
H
H
G
A
G
S
S
G
L
S
F
A
V
L
S
Conservation
Percent
Protein Identity:
100
98.4
90.3
98.4
N.A.
97.9
97.9
N.A.
86.2
84.7
85.2
20.4
N.A.
47.4
52
42.4
59.5
Protein Similarity:
100
98.6
91.3
98.9
N.A.
99.4
99.4
N.A.
88.5
87.8
93
40.4
N.A.
67.2
70.9
58.8
72.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
13.3
0
N.A.
0
13.3
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
13.3
0
N.A.
0
20
40
20
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
N.A.
36.1
Protein Similarity:
60.3
N.A.
N.A.
N.A.
N.A.
51.3
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
13
7
7
0
0
0
0
0
13
0
0
7
% A
% Cys:
0
0
7
0
0
7
0
7
0
0
0
0
13
0
0
% C
% Asp:
13
0
0
7
7
7
50
7
7
0
0
0
7
7
0
% D
% Glu:
44
0
38
0
0
0
0
0
0
7
0
0
0
0
7
% E
% Phe:
7
0
7
0
7
0
7
0
44
0
13
0
0
0
0
% F
% Gly:
7
0
13
0
50
7
0
19
7
0
0
0
13
0
44
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
7
% H
% Ile:
7
7
13
13
0
7
7
7
0
7
7
0
7
0
7
% I
% Lys:
0
0
0
13
0
38
7
0
0
0
7
7
38
7
0
% K
% Leu:
0
13
7
0
0
0
7
0
7
0
7
7
13
13
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% M
% Asn:
0
38
7
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
13
0
0
7
0
7
0
% P
% Gln:
0
0
0
0
7
7
7
7
0
0
0
7
0
0
0
% Q
% Arg:
0
7
7
0
13
0
0
7
7
44
13
0
0
19
0
% R
% Ser:
0
0
0
7
0
13
19
7
7
13
0
7
0
44
7
% S
% Thr:
0
7
7
44
0
13
0
38
0
7
0
0
0
0
0
% T
% Val:
0
13
0
0
7
0
0
7
13
7
57
7
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
0
0
0
0
0
7
0
44
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _