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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IPP All Species: 29.39
Human Site: S555 Identified Species: 53.89
UniProt: Q9Y573 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y573 NP_005888.1 584 65261 S555 L A P G T L D S V E V Y N P H
Chimpanzee Pan troglodytes XP_001159408 556 62209 V529 P R A G M C V V A V N G L L Y
Rhesus Macaque Macaca mulatta XP_001104247 584 65184 S555 L A P G T L D S V E V Y N P H
Dog Lupus familis XP_532595 584 65251 S555 L A P G T L D S V E V Y N P H
Cat Felis silvestris
Mouse Mus musculus P28575 584 65323 S555 L A P G T L D S V E V Y N P H
Rat Rattus norvegicus Q8R2H4 568 63244 Y540 L L S S I E C Y D P I I D S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508662 584 65477 S555 L A P V T L D S V E V Y N P H
Chicken Gallus gallus XP_422442 611 67297 S582 A A P V T S D S V E V Y N P H
Frog Xenopus laevis Q6NRH0 564 63190 Y536 L L N S V E C Y D P L I D S W
Zebra Danio Brachydanio rerio Q5U374 564 62914 D537 L S S I E C Y D P V I D S W E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 R586 D P E T N Q W R L C G C M N Y
Honey Bee Apis mellifera XP_001120870 595 66312 T564 R T Q I T I S T V E C Y D P H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797770 583 65047 T554 T A P P T L D T M E C Y D P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 98.9 97.2 N.A. 87.6 36.2 N.A. 91.4 79.5 36.1 34.5 N.A. 34.3 38.9 N.A. 45
Protein Similarity: 100 95.2 99.8 98.9 N.A. 92.1 53.5 N.A. 95.5 87.4 53.5 53.2 N.A. 51.6 56.8 N.A. 61.6
P-Site Identity: 100 6.6 100 100 N.A. 100 6.6 N.A. 93.3 80 6.6 6.6 N.A. 0 40 N.A. 53.3
P-Site Similarity: 100 13.3 100 100 N.A. 100 20 N.A. 93.3 80 20 26.6 N.A. 13.3 60 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 54 8 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 16 16 0 0 8 16 8 0 0 0 % C
% Asp: 8 0 0 0 0 0 54 8 16 0 0 8 31 0 0 % D
% Glu: 0 0 8 0 8 16 0 0 0 62 0 0 0 0 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 39 0 0 0 0 0 0 8 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 % H
% Ile: 0 0 0 16 8 8 0 0 0 0 16 16 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 62 16 0 0 0 47 0 0 8 0 8 0 8 8 0 % L
% Met: 0 0 0 0 8 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 0 0 8 0 8 0 0 0 0 0 8 0 47 8 0 % N
% Pro: 8 8 54 8 0 0 0 0 8 16 0 0 0 62 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 8 16 16 0 8 8 47 0 0 0 0 8 16 0 % S
% Thr: 8 8 0 8 62 0 0 16 0 0 0 0 0 0 0 % T
% Val: 0 0 0 16 8 0 8 8 54 16 47 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 16 % W
% Tyr: 0 0 0 0 0 0 8 16 0 0 0 62 0 0 16 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _