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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPP
All Species:
23.33
Human Site:
Y259
Identified Species:
42.78
UniProt:
Q9Y573
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y573
NP_005888.1
584
65261
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Chimpanzee
Pan troglodytes
XP_001159408
556
62209
I240
P
Q
R
L
L
K
Y
I
E
G
V
S
D
F
N
Rhesus Macaque
Macaca mulatta
XP_001104247
584
65184
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Dog
Lupus familis
XP_532595
584
65251
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P28575
584
65323
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Rat
Rattus norvegicus
Q8R2H4
568
63244
C248
F
I
R
C
S
L
Q
C
R
D
L
V
D
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508662
584
65477
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
F
P
Chicken
Gallus gallus
XP_422442
611
67297
Y286
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Frog
Xenopus laevis
Q6NRH0
564
63190
C244
L
I
R
C
S
L
Q
C
R
D
L
V
D
E
A
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
C244
L
I
R
C
S
L
P
C
R
D
L
V
D
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
E285
D
L
L
V
R
S
D
E
A
C
R
D
L
V
D
Honey Bee
Apis mellifera
XP_001120870
595
66312
R266
A
S
L
I
V
A
L
R
S
I
Q
K
D
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797770
583
65047
S258
D
Y
H
P
R
R
K
S
Q
A
S
T
K
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
98.9
97.2
N.A.
87.6
36.2
N.A.
91.4
79.5
36.1
34.5
N.A.
34.3
38.9
N.A.
45
Protein Similarity:
100
95.2
99.8
98.9
N.A.
92.1
53.5
N.A.
95.5
87.4
53.5
53.2
N.A.
51.6
56.8
N.A.
61.6
P-Site Identity:
100
33.3
100
100
N.A.
100
0
N.A.
93.3
100
6.6
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
93.3
100
26.6
20
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
8
8
0
0
0
0
24
% A
% Cys:
0
0
0
24
0
0
0
24
47
8
0
47
0
0
0
% C
% Asp:
16
0
0
0
0
0
8
0
0
24
0
8
39
0
8
% D
% Glu:
0
0
0
0
0
0
47
8
8
47
0
0
0
24
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
24
0
8
0
0
0
8
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
54
8
0
0
0
0
8
54
0
0
% K
% Leu:
62
8
16
54
54
24
8
0
0
0
24
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
47
% P
% Gln:
0
54
0
0
0
0
16
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
31
0
16
8
0
8
24
0
8
0
0
0
0
% R
% Ser:
0
8
0
0
24
8
0
8
8
0
8
8
0
39
8
% S
% Thr:
0
0
47
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
54
24
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _