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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM22 All Species: 17.88
Human Site: S46 Identified Species: 32.78
UniProt: Q9Y584 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y584 NP_037469.2 194 20031 S46 P R L L E P G S L G G I P S P
Chimpanzee Pan troglodytes XP_001153337 194 19956 S46 P R L L E P G S L G G I P S P
Rhesus Macaque Macaca mulatta XP_001117224 127 13282
Dog Lupus familis XP_537758 193 20102 S45 P R L L E P S S L G G I P S P
Cat Felis silvestris
Mouse Mus musculus Q9CQ85 194 20096 S46 P R L L E P G S L G G I P S P
Rat Rattus norvegicus Q9JKW1 192 19899 S44 P R L L E P G S L G G I P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509430 190 19694 G45 L E P G V L G G I P S P A K S
Chicken Gallus gallus
Frog Xenopus laevis Q5U4U5 184 19370 I44 L G G I P T P I K P E E Q K M
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IN78 195 21014 P46 Y R E N I I I P K S N G P V K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAQ9 213 23444 P64 P E R T P I K P I Q M L T L P
Sea Urchin Strong. purpuratus XP_797371 112 11716
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12328 207 21845 G53 S V V S G V T G F A L G G V L
Red Bread Mold Neurospora crassa Q9C1E8 194 19493 M44 S C F A K T V M S G G A G F A
Conservation
Percent
Protein Identity: 100 98.9 62.3 93.8 N.A. 95.3 93.8 N.A. 87.1 N.A. 78.8 N.A. N.A. 45.1 N.A. 37.5 34.5
Protein Similarity: 100 99.4 64.4 94.8 N.A. 97.4 96.3 N.A. 91.2 N.A. 85 N.A. N.A. 61.5 N.A. 53 43.3
P-Site Identity: 100 100 0 93.3 N.A. 100 100 N.A. 6.6 N.A. 0 N.A. N.A. 13.3 N.A. 13.3 0
P-Site Similarity: 100 100 0 93.3 N.A. 100 100 N.A. 13.3 N.A. 6.6 N.A. N.A. 13.3 N.A. 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 32.4
Protein Similarity: N.A. N.A. N.A. N.A. 38.1 41.7
P-Site Identity: N.A. N.A. N.A. N.A. 0 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 0 8 8 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 16 8 0 39 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 0 8 8 8 8 0 39 16 0 47 47 16 16 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 16 8 8 16 0 0 39 0 0 0 % I
% Lys: 0 0 0 0 8 0 8 0 16 0 0 0 0 16 8 % K
% Leu: 16 0 39 39 0 8 0 0 39 0 8 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 8 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 47 0 8 0 16 39 8 16 0 16 0 8 47 0 47 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 47 8 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 0 0 8 0 0 8 39 8 8 8 0 0 39 8 % S
% Thr: 0 0 0 8 0 16 8 0 0 0 0 0 8 0 0 % T
% Val: 0 8 8 0 8 8 8 0 0 0 0 0 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _