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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM22
All Species:
5.45
Human Site:
T149
Identified Species:
10
UniProt:
Q9Y584
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.67
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y584
NP_037469.2
194
20031
T149
L
I
E
S
Y
R
G
T
S
D
W
K
N
S
V
Chimpanzee
Pan troglodytes
XP_001153337
194
19956
T149
L
I
E
S
H
R
G
T
S
D
W
K
N
S
V
Rhesus Macaque
Macaca mulatta
XP_001117224
127
13282
S91
D
W
K
N
S
V
I
S
G
C
I
T
G
G
A
Dog
Lupus familis
XP_537758
193
20102
K148
L
V
E
S
Y
R
G
K
S
D
W
K
N
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ85
194
20096
K149
L
V
E
S
Y
R
G
K
S
D
W
K
N
S
V
Rat
Rattus norvegicus
Q9JKW1
192
19899
K147
L
V
E
S
Y
R
G
K
S
D
W
K
N
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509430
190
19694
K145
L
V
E
S
Y
R
G
K
S
D
W
K
N
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U4U5
184
19370
K139
L
V
E
S
Y
R
G
K
S
D
W
K
N
S
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IN78
195
21014
V148
T
I
E
S
H
R
G
V
T
D
W
K
N
G
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAQ9
213
23444
K167
A
L
E
T
I
R
A
K
S
D
W
R
N
G
T
Sea Urchin
Strong. purpuratus
XP_797371
112
11716
I77
N
S
P
I
A
G
C
I
T
G
G
L
I
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12328
207
21845
K149
V
I
E
S
L
R
A
K
N
D
I
Y
N
G
V
Red Bread Mold
Neurospora crassa
Q9C1E8
194
19493
K143
G
I
E
G
L
R
A
K
N
D
L
G
N
G
V
Conservation
Percent
Protein Identity:
100
98.9
62.3
93.8
N.A.
95.3
93.8
N.A.
87.1
N.A.
78.8
N.A.
N.A.
45.1
N.A.
37.5
34.5
Protein Similarity:
100
99.4
64.4
94.8
N.A.
97.4
96.3
N.A.
91.2
N.A.
85
N.A.
N.A.
61.5
N.A.
53
43.3
P-Site Identity:
100
93.3
0
86.6
N.A.
86.6
86.6
N.A.
86.6
N.A.
86.6
N.A.
N.A.
60
N.A.
40
0
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
93.3
N.A.
N.A.
73.3
N.A.
60
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
32.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
41.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
24
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
85
0
0
0
0
0
% D
% Glu:
0
0
85
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
8
62
0
8
8
8
8
8
47
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
39
0
8
8
0
8
8
0
0
16
0
8
0
0
% I
% Lys:
0
0
8
0
0
0
0
62
0
0
0
62
0
0
0
% K
% Leu:
54
8
0
0
16
0
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
16
0
0
0
85
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
85
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
8
0
70
8
0
0
8
62
0
0
0
0
54
0
% S
% Thr:
8
0
0
8
0
0
0
16
16
0
0
8
0
0
16
% T
% Val:
8
39
0
0
0
8
0
8
0
0
0
0
0
0
70
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
70
0
0
0
0
% W
% Tyr:
0
0
0
0
47
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _