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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM22
All Species:
24.55
Human Site:
Y106
Identified Species:
45
UniProt:
Q9Y584
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y584
NP_037469.2
194
20031
Y106
G
F
D
P
K
D
P
Y
R
T
P
T
A
K
E
Chimpanzee
Pan troglodytes
XP_001153337
194
19956
Y106
G
F
D
P
K
D
P
Y
R
T
P
T
A
K
E
Rhesus Macaque
Macaca mulatta
XP_001117224
127
13282
L48
T
P
T
A
K
E
V
L
K
D
M
G
Q
R
G
Dog
Lupus familis
XP_537758
193
20102
Y105
G
F
D
P
K
D
P
Y
R
T
P
T
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ85
194
20096
Y106
G
F
D
P
K
D
P
Y
R
T
P
T
A
K
E
Rat
Rattus norvegicus
Q9JKW1
192
19899
Y104
G
F
D
P
K
D
P
Y
R
T
P
T
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509430
190
19694
Y102
G
F
D
P
K
D
P
Y
R
T
P
T
A
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U4U5
184
19370
L96
G
F
D
P
K
D
P
L
R
T
P
T
A
K
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IN78
195
21014
E105
M
A
D
P
F
A
N
E
K
K
Q
T
A
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAQ9
213
23444
T124
S
M
V
G
G
D
P
T
K
Q
L
T
L
K
Q
Sea Urchin
Strong. purpuratus
XP_797371
112
11716
M34
A
R
D
V
L
K
D
M
G
K
Q
C
L
F
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12328
207
21845
P106
V
Q
Q
I
S
D
L
P
F
R
Q
Q
M
K
L
Red Bread Mold
Neurospora crassa
Q9C1E8
194
19493
P100
P
V
D
L
S
S
M
P
L
K
E
Q
L
K
H
Conservation
Percent
Protein Identity:
100
98.9
62.3
93.8
N.A.
95.3
93.8
N.A.
87.1
N.A.
78.8
N.A.
N.A.
45.1
N.A.
37.5
34.5
Protein Similarity:
100
99.4
64.4
94.8
N.A.
97.4
96.3
N.A.
91.2
N.A.
85
N.A.
N.A.
61.5
N.A.
53
43.3
P-Site Identity:
100
100
6.6
100
N.A.
100
93.3
N.A.
100
N.A.
93.3
N.A.
N.A.
33.3
N.A.
26.6
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
46.6
N.A.
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.6
32.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
41.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
0
0
0
0
0
0
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
77
0
0
70
8
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
62
% E
% Phe:
0
54
0
0
8
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
54
0
0
8
8
0
0
0
8
0
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
62
8
0
0
24
24
0
0
0
70
0
% K
% Leu:
0
0
0
8
8
0
8
16
8
0
8
0
24
0
8
% L
% Met:
8
8
0
0
0
0
8
8
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
62
0
0
62
16
0
0
54
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
8
24
16
8
0
8
% Q
% Arg:
0
8
0
0
0
0
0
0
54
8
0
0
0
24
0
% R
% Ser:
8
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
8
0
0
0
0
8
0
54
0
70
0
0
0
% T
% Val:
8
8
8
8
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _