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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM22 All Species: 39.09
Human Site: Y125 Identified Species: 71.67
UniProt: Q9Y584 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y584 NP_037469.2 194 20031 Y125 M G Q R G M S Y A K N F A I V
Chimpanzee Pan troglodytes XP_001153337 194 19956 Y125 M G Q R G M S Y A K N F A I V
Rhesus Macaque Macaca mulatta XP_001117224 127 13282 A67 K N F A I V G A M F S C T E C
Dog Lupus familis XP_537758 193 20102 Y124 M G Q R G M S Y A K N F A I V
Cat Felis silvestris
Mouse Mus musculus Q9CQ85 194 20096 Y125 M G Q R G M S Y A K N F A I V
Rat Rattus norvegicus Q9JKW1 192 19899 Y123 M G Q R G M S Y A K N F A I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509430 190 19694 Y121 M G Q R G M S Y A K N F A L V
Chicken Gallus gallus
Frog Xenopus laevis Q5U4U5 184 19370 Y115 M G Q R G M S Y A K N F A I V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IN78 195 21014 Y124 M R S T T H S Y A K N F A L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NAQ9 213 23444 Y143 M S S R M K S Y G K N F G S I
Sea Urchin Strong. purpuratus XP_797371 112 11716 A53 A M I G A M F A C T E C L V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12328 207 21845 S125 M G K K S Y S S A K N F G Y I
Red Bread Mold Neurospora crassa Q9C1E8 194 19493 T119 M G Q R S Y S T A K N F A K V
Conservation
Percent
Protein Identity: 100 98.9 62.3 93.8 N.A. 95.3 93.8 N.A. 87.1 N.A. 78.8 N.A. N.A. 45.1 N.A. 37.5 34.5
Protein Similarity: 100 99.4 64.4 94.8 N.A. 97.4 96.3 N.A. 91.2 N.A. 85 N.A. N.A. 61.5 N.A. 53 43.3
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 93.3 N.A. 100 N.A. N.A. 53.3 N.A. 46.6 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 N.A. 100 N.A. N.A. 66.6 N.A. 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.6 32.4
Protein Similarity: N.A. N.A. N.A. N.A. 38.1 41.7
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 73.3
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 8 0 0 16 77 0 0 0 70 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 16 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 8 % E
% Phe: 0 0 8 0 0 0 8 0 0 8 0 85 0 0 0 % F
% Gly: 0 70 0 8 54 0 8 0 8 0 0 0 16 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 8 0 0 0 0 0 0 0 0 47 24 % I
% Lys: 8 0 8 8 0 8 0 0 0 85 0 0 0 8 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 8 16 0 % L
% Met: 85 8 0 0 8 62 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 85 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 70 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 16 0 16 0 85 8 0 0 8 0 0 8 0 % S
% Thr: 0 0 0 8 8 0 0 8 0 8 0 0 8 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 62 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 16 0 70 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _