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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4S1
All Species:
29.7
Human Site:
S41
Identified Species:
50.26
UniProt:
Q9Y587
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y587
NP_001121598.1
144
17005
S41
E
V
I
K
S
C
L
S
R
S
N
E
Q
C
S
Chimpanzee
Pan troglodytes
XP_522814
159
18485
S41
E
V
I
K
S
C
L
S
R
S
N
E
Q
C
S
Rhesus Macaque
Macaca mulatta
XP_001094284
157
18652
S41
E
V
I
K
S
C
L
S
R
S
N
E
Q
C
P
Dog
Lupus familis
XP_850275
144
16957
S41
E
V
I
K
S
C
L
S
R
S
S
E
Q
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL1
144
16799
S41
E
V
S
K
S
C
L
S
R
S
S
E
Q
C
S
Rat
Rattus norvegicus
P62744
142
16999
V41
E
V
H
A
V
V
T
V
R
D
A
K
H
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512751
220
25891
S117
E
V
I
K
N
C
L
S
R
S
K
E
Q
C
S
Chicken
Gallus gallus
XP_421226
144
17052
S41
E
V
I
K
H
C
L
S
R
S
K
D
Q
C
S
Frog
Xenopus laevis
NP_001089698
144
16961
S41
D
I
I
R
L
C
L
S
R
S
K
D
Q
C
S
Zebra Danio
Brachydanio rerio
NP_001003826
140
16307
A41
D
V
V
R
G
C
L
A
R
R
K
E
E
C
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308286
143
16921
A42
E
I
V
R
K
C
L
A
R
N
D
Q
Q
C
S
Maize
Zea mays
O50016
132
15996
N41
E
V
H
R
L
V
V
N
R
D
P
K
F
T
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
A43
D
L
T
P
T
I
L
A
R
K
P
K
M
C
N
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
R42
I
H
R
L
V
A
P
R
D
Q
K
Y
Q
S
N
Conservation
Percent
Protein Identity:
100
69.8
81.5
97.9
N.A.
95.8
43
N.A.
56.8
84.7
77.7
75
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
85.9
100
N.A.
97.9
66.6
N.A.
62.2
95.1
93.7
86.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
20
N.A.
86.6
80
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
33.3
N.A.
93.3
86.6
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
55.5
38.1
N.A.
N.A.
37.8
42.3
Protein Similarity:
83.3
61.8
N.A.
N.A.
63.4
64.5
P-Site Identity:
46.6
20
N.A.
N.A.
20
6.6
P-Site Similarity:
93.3
53.3
N.A.
N.A.
60
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
22
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
72
0
0
0
0
0
0
0
79
0
% C
% Asp:
22
0
0
0
0
0
0
0
8
15
8
15
0
0
0
% D
% Glu:
72
0
0
0
0
0
0
0
0
0
0
50
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
15
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
15
50
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
8
0
0
0
0
8
36
22
0
0
0
% K
% Leu:
0
8
0
8
15
0
79
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
0
8
0
8
22
0
0
0
29
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
15
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
72
0
0
% Q
% Arg:
0
0
8
29
0
0
0
8
93
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
36
0
0
58
0
58
15
0
0
8
65
% S
% Thr:
0
0
8
0
8
0
8
0
0
0
0
0
0
15
0
% T
% Val:
0
72
15
0
15
15
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _