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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP4S1 All Species: 29.39
Human Site: S43 Identified Species: 49.74
UniProt: Q9Y587 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y587 NP_001121598.1 144 17005 S43 I K S C L S R S N E Q C S F I
Chimpanzee Pan troglodytes XP_522814 159 18485 S43 I K S C L S R S N E Q C S F I
Rhesus Macaque Macaca mulatta XP_001094284 157 18652 S43 I K S C L S R S N E Q C P F T
Dog Lupus familis XP_850275 144 16957 S43 I K S C L S R S S E Q C S F I
Cat Felis silvestris
Mouse Mus musculus Q9WVL1 144 16799 S43 S K S C L S R S S E Q C S F I
Rat Rattus norvegicus P62744 142 16999 D43 H A V V T V R D A K H T N F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512751 220 25891 S119 I K N C L S R S K E Q C S F I
Chicken Gallus gallus XP_421226 144 17052 S43 I K H C L S R S K D Q C S F I
Frog Xenopus laevis NP_001089698 144 16961 S43 I R L C L S R S K D Q C S F I
Zebra Danio Brachydanio rerio NP_001003826 140 16307 R43 V R G C L A R R K E E C S F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002308286 143 16921 N44 V R K C L A R N D Q Q C S F V
Maize Zea mays O50016 132 15996 D43 H R L V V N R D P K F T N F V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35181 156 18134 K45 T P T I L A R K P K M C N I I
Red Bread Mold Neurospora crassa Q7SAQ1 143 16937 Q44 R L V A P R D Q K Y Q S N F V
Conservation
Percent
Protein Identity: 100 69.8 81.5 97.9 N.A. 95.8 43 N.A. 56.8 84.7 77.7 75 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.5 85.9 100 N.A. 97.9 66.6 N.A. 62.2 95.1 93.7 86.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 93.3 N.A. 86.6 13.3 N.A. 86.6 80 73.3 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 93.3 33.3 N.A. 93.3 86.6 86.6 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 55.5 38.1 N.A. N.A. 37.8 42.3
Protein Similarity: 83.3 61.8 N.A. N.A. 63.4 64.5
P-Site Identity: 46.6 13.3 N.A. N.A. 26.6 13.3
P-Site Similarity: 93.3 53.3 N.A. N.A. 53.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 22 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 72 0 0 0 0 0 0 0 79 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 15 8 15 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 50 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 93 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 15 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 50 0 0 8 0 0 0 0 0 0 0 0 0 8 58 % I
% Lys: 0 50 8 0 0 0 0 8 36 22 0 0 0 0 0 % K
% Leu: 0 8 15 0 79 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 8 22 0 0 0 29 0 0 % N
% Pro: 0 8 0 0 8 0 0 0 15 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 8 72 0 0 0 0 % Q
% Arg: 8 29 0 0 0 8 93 8 0 0 0 0 0 0 0 % R
% Ser: 8 0 36 0 0 58 0 58 15 0 0 8 65 0 0 % S
% Thr: 8 0 8 0 8 0 0 0 0 0 0 15 0 0 8 % T
% Val: 15 0 15 15 8 8 0 0 0 0 0 0 0 0 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _