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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP4S1
All Species:
24.24
Human Site:
T33
Identified Species:
41.03
UniProt:
Q9Y587
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y587
NP_001121598.1
144
17005
T33
N
K
R
T
L
L
E
T
E
V
I
K
S
C
L
Chimpanzee
Pan troglodytes
XP_522814
159
18485
T33
N
K
R
T
L
L
E
T
E
V
I
K
S
C
L
Rhesus Macaque
Macaca mulatta
XP_001094284
157
18652
T33
N
K
R
T
L
L
E
T
E
V
I
K
S
C
L
Dog
Lupus familis
XP_850275
144
16957
T33
N
K
R
T
L
L
E
T
E
V
I
K
S
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL1
144
16799
T33
N
K
R
A
L
L
E
T
E
V
S
K
S
C
L
Rat
Rattus norvegicus
P62744
142
16999
E33
D
E
K
Q
K
L
I
E
E
V
H
A
V
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512751
220
25891
A109
N
K
R
I
L
L
E
A
E
V
I
K
N
C
L
Chicken
Gallus gallus
XP_421226
144
17052
A33
H
K
R
T
M
L
E
A
E
V
I
K
H
C
L
Frog
Xenopus laevis
NP_001089698
144
16961
S33
Q
R
R
T
L
L
E
S
D
I
I
R
L
C
L
Zebra Danio
Brachydanio rerio
NP_001003826
140
16307
A33
G
K
R
A
A
L
E
A
D
V
V
R
G
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308286
143
16921
G34
E
E
R
R
A
L
E
G
E
I
V
R
K
C
L
Maize
Zea mays
O50016
132
15996
Y33
S
E
K
H
K
V
E
Y
E
V
H
R
L
V
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35181
156
18134
K35
G
E
K
A
K
I
V
K
D
L
T
P
T
I
L
Red Bread Mold
Neurospora crassa
Q7SAQ1
143
16937
E34
E
K
I
K
L
K
G
E
I
H
R
L
V
A
P
Conservation
Percent
Protein Identity:
100
69.8
81.5
97.9
N.A.
95.8
43
N.A.
56.8
84.7
77.7
75
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.5
85.9
100
N.A.
97.9
66.6
N.A.
62.2
95.1
93.7
86.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
20
N.A.
80
73.3
53.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
40
N.A.
86.6
86.6
86.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
55.5
38.1
N.A.
N.A.
37.8
42.3
Protein Similarity:
83.3
61.8
N.A.
N.A.
63.4
64.5
P-Site Identity:
40
20
N.A.
N.A.
6.6
13.3
P-Site Similarity:
66.6
60
N.A.
N.A.
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
22
15
0
0
22
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
0
% C
% Asp:
8
0
0
0
0
0
0
0
22
0
0
0
0
0
0
% D
% Glu:
15
29
0
0
0
0
79
15
72
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
8
15
0
8
0
0
% H
% Ile:
0
0
8
8
0
8
8
0
8
15
50
0
0
8
0
% I
% Lys:
0
65
22
8
22
8
0
8
0
0
0
50
8
0
0
% K
% Leu:
0
0
0
0
58
79
0
0
0
8
0
8
15
0
79
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
43
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% P
% Gln:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
72
8
0
0
0
0
0
0
8
29
0
0
0
% R
% Ser:
8
0
0
0
0
0
0
8
0
0
8
0
36
0
0
% S
% Thr:
0
0
0
43
0
0
0
36
0
0
8
0
8
0
8
% T
% Val:
0
0
0
0
0
8
8
0
0
72
15
0
15
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _